ID A0A401SH84_CHIPU Unreviewed; 2727 AA.
AC A0A401SH84;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=chiPu_0008155 {ECO:0000313|EMBL:GCC29713.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC29713.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC29713.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Cell junction, desmosome
CC {ECO:0000256|ARBA:ARBA00004568}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004236}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC29713.1}.
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DR EMBL; BEZZ01000264; GCC29713.1; -; Genomic_DNA.
DR STRING; 137246.A0A401SH84; -.
DR OMA; ETKERKC; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0030057; C:desmosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 3.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR23169:SF26; DESMOPLAKIN; 1.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR Pfam; PF00681; Plectin; 8.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21019; Spectrin_3; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00250; PLEC; 17.
DR SMART; SM00150; SPEC; 2.
DR SUPFAM; SSF75399; Plakin repeat; 4.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 514..571
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 2680..2711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 357..391
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 843..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1069..1613
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1646..1821
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2727 AA; 314571 MW; 618477122AB201D4 CRC64;
MSLHGSQTAL NRRSVTDRHY TFRSSGDYST RSDGAGDVFT SPIHLQYGAG GGDLHLSGQH
PYGLGSGTGG GSELLGTTTT TRMTYSSKNP RISESRSYNM VETAPYSSKM DSLKRQHNWI
QSMTDECANN LNRAEILLQE DLDAFDVGLH GRHRIEIDEL LKVAGEQLAI IEGYANDLKR
SGKPYESIQK SVNFHRNQMR AISKAITERM VDRTRTLRPQ RSKRSWDEGL SRSTKELFSW
LHQQKSLMDM QDWGVDATSV ERQINEQQNY HRNLEDFRWK IDKARMEQQG NFSESSREHM
QALQNEYDSM LKASTERLEQ LRKLQNIISA TSNEIMWIND REEEELVHDW SDKNTRIAEK
QEAFSMMMSK LEEKEKQLNR LKQDGDQLIA NNHPAADKIE AYIDTLQTQW SWILQLTKCI
EVHLKENSNY FQFFEDAQAT ETSLKKMQDS LRKKFVSDRS TSLPQLEKMI TESEKDKEKI
HEFKRQVSNL VNKSKKIVQL KPRNPPISAD QRTSNQIVLK ALCDYKQDQR VVHRGDECIL
LDNSQRSKWR VIGPGGMEMM VPSVCLLIPP PNSGAIDLAN KIDQYYEAIL ALWNQLYINM
KSLVSWQYCM MDVEKIRSWT MSVLRTMSRE DYELVIKNLE KNFQTFQMYS KTSEYFTDAD
KRKLESDFGS SKTHYVNLVT VLEEERKNNR GPVIIQPVAT PPKVDVNFQQ ELQKIRRRLE
QNEYKMMQKI HLLIDADAHM DFAQRMSELE LAQDELNTID DDFVSLQKTW YNSPSASSES
RGYFETEFGL IGQRLKNGSD FSSAYLERMK ALKLLFQNIL EAEDVIKVYE ARLTEEETVP
MSLDKIESYR NNLKKMKSEL DQKKNLIMSM QQNMQESLRI NDDIMPSFYK CDIDLTKYNE
KVTQLSDRWQ RINKEIDSRY LDLDKEYRQL KDYGDLFQNL SKWIDATKQK QDGLQVNRFG
DTNAIVDQLN EQKKLYAEIK GKRGNVEAYQ KHADLCATSV KDYELQLASY SAGLETLLNI
PIKRQLAQSI SSKILHESAD LQSRYIELLT RSGDYYKYLS EMLKNMEEVK IKNTKIELLE
EALKHAQDEN ADSVQQKRFL DQHLSQVQTE YADFRKRIMV LEEQKRNVEL DRDTIKQRED
SYLLQIKETH EKITKLTLEI DEERRKRKAA ENWYDQQKNE HDSAFRIKQK ELDEIVLIKL
EIEKSIKDKE RELEKLKNAF QEESLKRRQF ESELDELRVK YEQENRILKS QVEREVHERE
TIVERLTIKK EDDIATLKIQ LEKALNEKRN LMEEIERLRS SIRETEFNRK KAEKDSLQQK
SACIEESRRR EELEREIQTL SKLKTDETLR FKSLQQDTSK AIQDKGKEIE KLRILLEEEV
NKRKHLENEN DKLKQQQIDF QKKDTEKLTK LKTTEQEITV IKVEHEKVSR ERSKLQQEVE
RLQNNIREAN NAKYKIDEEL IQLRRNVLEE SSKRKRAEEE AERLGQKCKD HTFSITQLTE
QINHISIMKK NVEDDLSKQQ KAFDQQLKEK NISTGELNRL YADVETLRRQ LSQEQESTRQ
ACQRYEHVQK TSEEKTKALN ESLSEIDRLR SVVENLTKER LKLEEELRNL KSNFDDFKRF
RDDAEGDKSR TISELRQQLE LTYKRTTDLQ GLINELKNER EKLRLEVETF QKQALEATNM
IQQTHSAQKE ILQEKESLLL KIKLLEQDKS RLQRYEDDLS RIKAQLEAES RLKQRLQDEI
DAVKSDLSYW KNQAEIRQLE KGKTSNEFEQ LKAEIDRLKL ELRMTEERYR QKLEESERTK
RSELEALRMK AKLEIEKLSQ EVPTFNKQTQ TENIVTVDSS KLLFEGVRKK VTANQLYDCQ
LIDKSTLDQL LRGQKTTMDV SDEIKLNLRG LENIAGVYSQ KNGEKLSMSE ATKRNILTPD
VALSLLEAQA ATGHIIDPNK NKKMTVDEAV AVGLVDYKDR DKLLAAEKAA TGFKDPFTGK
VISLYEAMKK DIVDRETGLR LFAAQIAAGG IIDSVNSVYL PKELAYKRGL IDAEMYQTLA
SPFDDSKIFV DPNTKTKVSY QQLKLACRTD PGTDLLLLPV EKHEIMIPGI RADVSVDHLV
EAKVIDKNTA AALVQGTVTV EQISDKYRGY LQGSSCISGI YVEATKEKLP IYHAMRKGLL
RQGTALELLE AQAATGFVVD PVNNQKLTVE DAAAKGIIGQ EFKSKLLSAE RAVTGYKDPE
TGNIISLFQA MRKGLIEHSH GIRLLEAQIA TGGIIDPKHS HRLPVDVAYK RNYFDEELNE
ILMDPADDTK GFFDPNTEEN LTYLQLVDRC ITDKSTGLCL LPLREKKKES KTTRSSAVRK
RRVVIVDPDT NQEMTVREAY HKDLIDYETF LELSEQEAEW EEITITGSDG TTRTVIVDRK
TGNQYDIEES LKKGLIDKKS LDAYRSGSMT LTQFADMFTD KINISTYNGS APNSLTNLNP
CLSPTIKITS FESLDDASPI AAIFDIETLE KITISEAIRR NIVDAITGQR LLEAQACTGG
IINPGNGQKL LIHDAVSQAI IDEDMGKRLK PAQKAYVGFE DVKSKKRLSA VEAMQENWLP
YEAGQRFLEY QMATGGLVVP NVSGRITVDE AVRKGFMGAK TAEKLKDTSS HSKSLTCPKT
KLKISYKEAV DRSMVEDKTG LRMLEAASFS TKGINSAYNA GGFSGPNSRS GSRSGSRSGS
RRGSFDATSY NVSVSTHTTH LSTSSMR
//
