ID A0A401SRS2_CHIPU Unreviewed; 362 AA.
AC A0A401SRS2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=FAM86 N-terminal domain-containing protein {ECO:0000259|Pfam:PF14904};
GN ORFNames=chiPu_0011543 {ECO:0000313|EMBL:GCC33076.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC33076.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC33076.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. EEF2KMT family. {ECO:0000256|ARBA:ARBA00005511}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC33076.1}.
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DR EMBL; BEZZ01000484; GCC33076.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401SRS2; -.
DR STRING; 137246.A0A401SRS2; -.
DR OMA; TGFFHST; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029426; FAM86_N.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF164; PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT; 1.
DR Pfam; PF14904; FAM86; 1.
DR Pfam; PF10294; Methyltransf_16; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 16..105
FT /note="FAM86 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14904"
SQ SEQUENCE 362 AA; 40641 MW; 2DD08EF976729EA0 CRC64;
MSRSARVGLA LGEAGRELVL VFQRAFFAMR RLDSLPMGEL EEMLKTSGDS MLLEQILQQT
VLHPVCNEYP PSVKYRRLFL AELIKKHEMT STEPLDDLYD ALGEVLRSEE LQMCHKNYFL
LSGENIRLGE NVAIISEGTT GLVTWEAALF FAEWAMENSE LFNCRTILEL GSGAGLTGIA
ICKTCTPKQY IFSDCHSNVL HQLRKNILTN GLLLDSESWS SKDCEVQLEN NNGSEGNQRP
KITVVGLDWS DATQEQVTEL QPDVIIATDV VYDPAVFLCL VSILEKFRIS AENQGSSTVV
YVASTIRNPE TYYQFKMELD KVGIGHQVIP GPTRAVFPYD KCTKIELLKI HHGTEMFAHH
LT
//
