ID A0A401SSY1_CHIPU Unreviewed; 1097 AA.
AC A0A401SSY1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN ORFNames=chiPu_0011970 {ECO:0000313|EMBL:GCC33500.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC33500.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC33500.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC33500.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BEZZ01000522; GCC33500.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401SSY1; -.
DR STRING; 137246.A0A401SSY1; -.
DR OMA; WIIEDQS; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05763; IgI_LRIG1-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00365; LRR_SD22; 7.
DR SMART; SM00369; LRR_TYP; 13.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS51450; LRR; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1097
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019066439"
FT TRANSMEM 789..815
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 484..583
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 588..677
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 682..768
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1055..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1097 AA; 121475 MW; D4FAE9848F9C3FB1 CRC64;
MSATARRLWM AALVLWASGA LALLGDREPP RACPARCSCA ARLLDCSRRK LSRGPAPLPA
WTVRLDLSHN RITSINSSLF NNLHNLHEVK ITHNELTEVP NFGIMASNIT ILSLSNNKIV
EVRSEQLTPF RSLETLDLSN NHISELKTFP PLQLRCLYIN NNKITSLDPG CFDNLSNTLQ
ILKLNRNKIL AIPSKMFKLS HLQQLELSRN KIKKVDGLTF QGLSALKSLK LQRNGISKLM
DGAFWGLSNI ETLQLDFNNL TEVTKGWLYG LLMLQQLNLS QNAINRINPD AWEFCQKLSE
LDVSFNELTR LEDSSFVGLS LLGQLYIGNN QVSYIADGAF GGLSSLHSLD LRNNEISWTI
EDMNGAFSEL SKLKKLGLQG NRIRSITRKA FSGLDALEYL DLSNNAIMSV QSNTFSQMKK
LHELYLNTTS LLCDCQLKWL HQWVTDNGFQ PFINASCAHP QWLKGKSIFA TKPEDFVCDD
FPKPEIIEQP ETQAAVKDSN VSFICSAASS SDSPMTFAWK KDNEVLHNGE IENYAHLRSQ
GGEVMEYTTI LRLRHVNFSS EGKYQCVISN HFGSSYSNKA KLTVNMLPSF TKSPTDLTIR
AGAMARLECA AIGHPTPQIA WQKDGGTDFP AARERRMHVM PEDDVFFIVD VKIEDIGIYS
CTAQNSAGAI STNATLTVLE TPSFVRPLVD KTVAKGETAV LQCIAAGSPP PRLNWTKDDS
PLTVTERHFF AAGNQLLIIV DSNLEDAGKY TCEMSNTLGT ERGHIRLNVI PIPNCDSTQS
AAPFEEDGWS TIGIVIIAVV CCVVGTSLVW VVIIYHTRRK SEDCSVTNTD ETNLPADIPS
YLSSQGTLSD HQEGYGRSEA GSHHQLMTSS MNGYLLQHRG SDDLCHIDNG SDTDLEGMAD
PLVFHDPDQA GSVYMGGTVY ESERLEGIHQ HDGNSDQVVA CANAYDDSSI NSKKKEYCQY
SQVPPEDPFD QAIAKIMVQI PSSNLFNSVQ TLHKGTPIGV PGSSRNSEKL PATMYGGTFG
KPLWRTLQDP YSDCTQPAVS PSLTLHHNPR ALLHSDSEAE EQSDNPPVSV TGQHNSTYER
NADKCRTPVF QPYRVNT
//
