ID A0A401STA7_CHIPU Unreviewed; 1559 AA.
AC A0A401STA7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
GN ORFNames=chiPu_0012072 {ECO:0000313|EMBL:GCC33602.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC33602.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC33602.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC33602.1}.
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DR EMBL; BEZZ01000532; GCC33602.1; -; Genomic_DNA.
DR STRING; 137246.A0A401STA7; -.
DR OMA; HESRWLE; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd00603; IPT_PCSR; 1.
DR CDD; cd01181; IPT_plexin_repeat3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR041362; TIG2_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF34; PLEXIN-A4; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 3.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF01833; TIG; 3.
DR Pfam; PF18020; TIG_2; 1.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 3.
DR SMART; SM00423; PSI; 3.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 2.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1559
FT /note="Sema domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019054246"
FT TRANSMEM 1188..1210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..499
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT COILED 1214..1241
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1559 AA; 174005 MW; 527999D7EF8EA08C CRC64;
MAVGRYCLTF LLLLTLASCC GGGSVVNQDY RTFKTDNPDW VFNHLAVDQS TGSVYLGAVN
RIYKLSSDLH PLITHQTGPD EDNPNCYPPR IVQPCNEPLR LTDNINKMLL IDQGERRLIA
CGSLYQGICK LLRLEDLFKL GEPYHKKEHY LSGVNDSGSV FGVIVSGQGS DAKLFVATAV
DGKPEYFPTI SSRLLASNAE ADEMFSFVFH DEFVASLIKI PSDTFTVIPD FDIYYIYGFS
SGAFVYFLTL QPELINTGPG SSRQQVYTSK LVRLCQADTT FNSYVEMPIG CVRDGVEYRL
LQAAHLAKAG PVLARSLGIQ ANRDDVLFAV FSKGQKRRSQ APDESVLCMF VLSSINERIK
DRLQSCYRGE GFLDLAWLKV KDIPCVPAPV PIDDSFCGLD INAPLGGSTL MQGIPLFSED
RDRMSSVISY VYNDHSLVFV GTKSGKLKKI RVDGPSHGAL QYETIQVVES GAILRDMSLS
VDRQYLYVMS EKQLTRVPVE ACGQYQTCSE CLGSGDPHCG WCVLHNTCTR KDKCKRSTEL
RRFASDIKQC VTLTVSPSNI SVSQYSVPLV LEAHNVPELS VGVNCTFEDF AEMDGLVIGN
MIQCISPAEK EVPRILTDKG DHQVVKLHLK SKETGMTFAS TSFVFYNCSV HHSCLSCVNS
PYRCHWCKYR HMCTHDPRTC SFQEGRVNIS EDCPQLLAAE KVLVPVGVVK PITLKSKNLP
QPQSGQRGYE CILNIHGVEQ RVPALRFNSS SVQCQNTSYS YEGTTINNLP VDLSVVWNGD
FSIDNPAHNQ VHLYKCGVMR ESCGLCLKAD PDFECGWCRG DGRCTLRQDC PASDEQWLEP
SGTNRKCTNP RITEVTQCEV GDGIMCEMGV ARHNQHTGFV EVCVEECKQE FMAKSTQLYS
FVLPTLTNLA PSKGPVSGGT MVTILGRNLD AGSDVSVMFE EQPCVFNRRF TGGIICNSTS
APRKGNFTVV VGVDKARIEK ELLFEYVDDP TIVKVEPEWS IVSGSTPVMV WGTNLDIIQH
PKIRANHNGV ETINTCTVQN STTMICQAPA LAISPNQQTD NTERPDEFGF ILDNVQTLLI
YNNTNFIYYP NPVFEPLSTS GVLELKPGSP IILKGHNLIP SIAAGNMKLN YTVLIGEKPC
TVTVSDTQLL CESPNLTGRH RILVRVGGLE YSPGTVHIFP DSPLSFPAII SIGAAGGLLI
IFIIVVLIAY KRKSRESDLT LKRLQMQMDN LESRVALECK EAFAELQTDI NELTSDLDGT
GIPFLDYRAY TMRVLFPGIE DHPVLRELEV PGYRQERVEK GLTLFGQLIN NKIFLLTFIR
TLESQRSFSM RDRGNVASLI MTVLQTKLEY ATDVLKQLLS DLIDKNLESK NHPKLLLRRT
ESVAEKMLTN WFTFLLYKFL KECAGEPLFM LFCAIKQQME KGPIDSITGE ARYSLSEDKL
IRQQIDYKTL VLYCVNPDNE NSPEISTKTL NCDTITQVKE KILDTIFKNL PCSHRPKAAD
MDLEWRQGRM ARVILQDEDV TTKIENDWKR LNTLAHYQGD RWFCSCSGSQ TNNSVQCCQ
//
