ID   A0A401SW94_CHIPU        Unreviewed;       756 AA.
AC   A0A401SW94;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Protein VAC14 homolog {ECO:0000256|ARBA:ARBA00013840};
GN   ORFNames=chiPu_0013126 {ECO:0000313|EMBL:GCC34651.1};
OS   Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC   Chiloscyllium.
OX   NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC34651.1, ECO:0000313|Proteomes:UP000287033};
RN   [1] {ECO:0000313|EMBL:GCC34651.1, ECO:0000313|Proteomes:UP000287033}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA   Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA   Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA   Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA   Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT   "Shark genomes provide insights into elasmobranch evolution and the origin
RT   of vertebrates.";
RL   Nat. Ecol. Evol. 2:1761-1771(2018).
CC   -!- SUBCELLULAR LOCATION: Microsome membrane
CC       {ECO:0000256|ARBA:ARBA00004524}.
CC   -!- SIMILARITY: Belongs to the VAC14 family.
CC       {ECO:0000256|ARBA:ARBA00010225}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GCC34651.1}.
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DR   EMBL; BEZZ01000620; GCC34651.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A401SW94; -.
DR   STRING; 137246.A0A401SW94; -.
DR   OMA; CYQHVSE; -.
DR   Proteomes; UP000287033; Unassembled WGS sequence.
DR   GO; GO:0070772; C:PAS complex; IEA:InterPro.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR026825; Vac14.
DR   InterPro; IPR021841; VAC14_Fig4p-bd.
DR   PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR   PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF12755; Vac14_Fab1_bd; 1.
DR   Pfam; PF11916; Vac14_Fig4_bd; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022848};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Microsome {ECO:0000256|ARBA:ARBA00022848};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          510..687
FT                   /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT                   /evidence="ECO:0000259|Pfam:PF11916"
FT   REGION          324..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          440..482
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          732..756
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..482
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   756 AA;  86093 MW;  03F3CC4B79880E0E CRC64;
     MRCFHSLLVR EFVAQNNTGQ IKHVIQILSQ EFALSQHPHS RKGGLIGLAA CSIALGKDSG
     LYLKELIEPV LTCFNDADSR LRYYACEALY NIVKVARGSV LPHFNVLFNG LSKLAADPDP
     NVKSGSELLD RLLKDIVTES SKFDLVAFVP LLRERIYSNN QYARQFIISW ILVLECVPDI
     NLLEYLPEIL DGLFQILGDN SREIRKMCET VLVEFLKEIK RNPSSVKFAE MANILVIHCQ
     ASDDLIQLTA MTWMREFIQL AGRAMLPYSS GILTAVLPCL SYDDRKKSIK EVANVCNQTL
     MKLIMPEDDG DNIRQFMLQQ LDGTADESSS SRKNSSDQSN MSQDLNTSNN TGESVTIDHS
     QEALDLDGIV LVLDRHLHDT VTGMMTRIAV LKWLYHLYIK TPRKMFRHTD SLFPMLLKTL
     SDESDEVILK DLEVLAEIAS SPAGQTEGQD SYESNSTQNS QSELNIPISS TPLNSSRPRT
     LECSPSTPTM NSYFFKFMVN LLKQFNNEKR LLETRGPFII RQLCLLLNAE NIFHSMAEIL
     LREEDLKFAS TMVQTLNSIL LTSTELFQLR NQLKDLRTTE SCNLFCGLYR SWCHNPVATV
     SLCFLTQNYK HAYDLIQKFG DLEVTIDFLT EVDKLVQLIE CPIFTYLRLQ LLDVENNPYL
     IKALYGLLML LPQSKAFQLL SQRLQCVPNP ELMRTTPSEK STAPNRQVPL EINYSDLLQH
     FEKVQNKHLE IRHQRAGRTD QLDRKHPRDT EANSSV
//