ID A0A401SXJ6_CHIPU Unreviewed; 699 AA.
AC A0A401SXJ6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Matrilin-4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=chiPu_0013594 {ECO:0000313|EMBL:GCC35113.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC35113.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC35113.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC35113.1}.
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DR EMBL; BEZZ01000666; GCC35113.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401SXJ6; -.
DR STRING; 137246.A0A401SXJ6; -.
DR OMA; DKRSCSM; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF14670; FXa_inhibition; 5.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00179; EGF_CA; 6.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 29..208
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 333..373
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 463..638
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 699 AA; 77072 MW; D47FF265322236FB CRC64;
MDGIQAAKRR QIKIRDRKEG KKCTTGPMDL LFIIDSSRSV RPFEFELMRN FVIDMINFLN
VGPAAGRVAL IQYSSQIQNV FSFKTFQKKA DMIKSVKEVI PLAQGTMTGL AIQYAMNVAF
TEEQGARPLA QKIPRVAIII TDGMPQDRVT EVAAEARESG IEIYAVGVQR AEISSLRAMA
SLPHEEHVFL VENFDLIDQF AKTFKDKLCS QDLCASESHG CEHICVTTPE SFHCACREGY
VLNPDKKTCT AIDLCSHGDH DCEQICISSP GSYKCSCREG FRLNPDKKTC SAVNLCALGA
HGCEHICVST PGSYRCRCRS GYTLNQDKKT CSAVDLCALG DHGCEHICVS TPGSYKCRCQ
PGYTLNQDKK TCSMVNYCSF GNHSCQHECV SILNGYYCTC RDGFELHDDG KTCKVVDMCN
TVEHGCEFKC VSTPGSYFCI CPPGRQLNED GKTCNRCSKA NIDLAFVIDG SKSVRPENFE
LVKKFVNNIV DALDISSQGT RVALVQYSSQ VRTEIPLGTH TTTAALKKAV NNVVYMEKGT
MTGLALKHMV ENVFTEAGGA RPGSQSQPRV GVVFTDGRSQ DSISEWAKKA KDAGITMYAV
GVGKAVEDEL REIASEPVDQ HFFYASDFSI IDQIAENLKV NICEEEVTGQ ETIKDPCACE
TLVAFQQDTL SLLEEFSQKL AQMTGRLDDL ENRLPKAVK
//
