ID A0A401T008_CHIPU Unreviewed; 2433 AA.
AC A0A401T008;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Nuclear receptor corepressor 1 {ECO:0000256|ARBA:ARBA00044171};
GN ORFNames=chiPu_0014464 {ECO:0000313|EMBL:GCC35974.1};
OS Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Orectolobiformes; Hemiscylliidae;
OC Chiloscyllium.
OX NCBI_TaxID=137246 {ECO:0000313|EMBL:GCC35974.1, ECO:0000313|Proteomes:UP000287033};
RN [1] {ECO:0000313|EMBL:GCC35974.1, ECO:0000313|Proteomes:UP000287033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30297745; DOI=.1038/s41559-018-0673-5;
RA Hara Y, Yamaguchi K, Onimaru K, Kadota M, Koyanagi M, Keeley SD, Tatsumi K,
RA Tanaka K, Motone F, Kageyama Y, Nozu R, Adachi N, Nishimura O, Nakagawa R,
RA Tanegashima C, Kiyatake I, Matsumoto R, Murakumo K, Nishida K, Terakita A,
RA Kuratani S, Sato K, Hyodo S Kuraku.S.;
RT "Shark genomes provide insights into elasmobranch evolution and the origin
RT of vertebrates.";
RL Nat. Ecol. Evol. 2:1761-1771(2018).
CC -!- SIMILARITY: Belongs to the N-CoR nuclear receptor corepressors family.
CC {ECO:0000256|ARBA:ARBA00010097}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCC35974.1}.
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DR EMBL; BEZZ01000768; GCC35974.1; -; Genomic_DNA.
DR STRING; 137246.A0A401T008; -.
DR OMA; AVIPPMX; -.
DR Proteomes; UP000287033; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR CDD; cd00167; SANT; 2.
DR Gene3D; 1.20.5.430; -; 1.
DR Gene3D; 1.20.58.1880; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR031557; N-CoR_GPS2_interact.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR PANTHER; PTHR13992; NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR; 1.
DR PANTHER; PTHR13992:SF5; NUCLEAR RECEPTOR COREPRESSOR 1; 1.
DR Pfam; PF15784; GPS2_interact; 1.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51294; HTH_MYB; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
DR PROSITE; PS51293; SANT; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000287033};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 401..452
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 578..632
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 578..628
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 581..632
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1169..1197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1302..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1700..1747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1759..1783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1855..1939
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1960..1982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1997..2064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2088..2209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2343..2378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2396..2433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..114
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..692
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..847
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..950
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1316..1333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1719..1747
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1857..1875
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1876..1919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1924..1939
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1997..2021
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2039..2064
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2088..2142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2146..2163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2433 AA; 271797 MW; EC6C0C26E5EE45C5 CRC64;
MIDCPKMSSS GYPQGQGPFG AEPTRYPTHA IRYNFSGRHQ QEFAVPDYRL QDSQLLQQQH
QQLRRRPSLL SEFHPASDRP QERRSGYEQS YHSVAGQPDH ESLESKRPRL EQESFSVKAD
VPSSPTTNQQ VGDEQDSSPS KLSKEELIQS MDRVDREIAK VEQQILKLKK KQQQLEEEAA
KPPEPEKPVS PPPVEPKHRS IVQIIYDENR KKAEEAHKIL EGLGPRVELP LYNQPSDTKI
YHENIKTNQI MRKKLILFFK RRNHARKQRE QKICQRYDQL MEVWEKKVER IENNPRRKAK
ESKTREYYEK QFPEIRKQRE QQERFQRVGQ RGAGLPATIA RSEHEISEII DGLSEQENNE
KQMRQLSVIP PMMYDTEQRR VKFLNMNGVM DDPMRVYKER QFINVWSEHE KEIFKEKFVQ
HPKNFGLIAS YLERKCVADC VLYYYLTKKN ENYKNLVRRN YGRRRGRNTQ QISRPSQEEK
ETEKEEEKVE KVEREEKDEK KEEEKDDKEE PQRETVKEKD KPDTAGEEPE EKEQSAPRGR
KTANSQGRRK GRILRSMAKE AITEEPPNPP PPPELAVTEP VETSRWTEEE MEVAKKGLVE
HGRNWAAIAK MVGTKSEAQC KNFYFNYKRR HNLDMLLQQH KLRVQQMSRR SREDREVSQC
ESIASTVSAQ EDEDNEVSNE EENPEDSEGA ENSSDTESAP SPSPVDTGKS SKESTEMNKL
TEEGLNPTSR SSPTIPPVSP AQAAASPELQ VKQEMNLGFE EPMEGQRGSE AEVKPVFEPQ
VKPKTEPVDV DMKPEENLQV KVEVDAKDKE FEKARQQETV ASELLDLPQP GSQVESHSDN
DSSATCSADE VEDGEPERQR MFSPESKSSL LKPLSSVLMT SAMKPVQMDI QQLQQRAAMI
PNMMAAPYAT TTAPVSGLAL FQRHIKAMHD SALQEEQMRQ RQEHMDAERR NSSSPNISGK
TCPILDREGK PFVYMPYHEA RRVMEQESQT TGARSASPYR LSPRESCKLS PQPEMNTLRY
SVPPVLQPAP HQMMQTTSEG GKLVITRPAR PSNIPSPPPL IPSTKPPLST EKPTFNMGGS
ISQVSSGTYL APHNQVAYNQ ETVKNTVGSI SLGLPRQQEP VKSGPLQFIK QEELSPRSQN
PQPEGLLSRA TYETNVVRGG PMANIQEASL TRSSPAGKVS AEPPSYRGSI TQGTPGLSQQ
GIAADTLLKG AISKLAAEES GSPEQSREEA ISKGHVIYES SSGHILSYDT IKNIREGTRS
PRTGPDVHGV KRTYDLMESG LSRVPVRESS VSAPYEGLIS RARESPHLSE SKDRAVPSGS
IMQGTPRASS ETYEESMKYG KQIKRESPPL RTFEGSITKG KPYEGVTTIK EMGRSIHEIP
RQESRKTPEI VQSSRSIVEG SISQGTPVKH ENQSAIKHDV KSLITASGKH PHPMHQLEMI
SEGVKIVERK YEDMKPADQL RGRHSAVVSS GTSVLRSTMH EASKSQLSPG LYEDPNARRT
PLGYPGFIPR GPPIVSRPQE GVMTSVKSTG HERKTTLVPT QRDNMSVKSP VSVVDPSATL
SPYDSLHGRG NPEYRSHVPH PFEQTMAFHR ALDPAYLFSR QLSPNPSYSS HYQLYAMENT
RQTILNDYIT SQQMQVITKP DGTRGMSPRE TLGVPYAAGS RAIIELGPVS HTILVPGGSS
TPPMERITYI PGNQAPYPGR YNHSPISPGH PAHMSATAAT AEREREKERE REREQRERER
EQRERERLAV TTCDLSYLRA GPEQTSRPSS HGYVRSPSPS VRTPETILQQ RPSIFQGANG
KGVITSLDAA TQSRIMQVPQ GALSMAQGLS TSRYNTAADA LAALVDAAAS APQIEMTKGK
ENKHEAPRVE EMTARRVSEQ QPNIHHQAPQ QPQSEHERRS VQSPYSSTAK GQGQSNYPES
IKDKAPPPKS RYEEELRTRG KTTITAANFI DVIITRQIAS DKDSRERGSH SSDSSSSVSS
HRYDMPSVDA IEVISPANSP VQSQEKAEPV QQETHKPSQG DGEPNTRGFD VPMSRYRMMQ
KSPSPQQQPP SSQPDSVYSS VPNPQVSKTH KLITLADHIH HIITQDFARN QPNSPSSQPP
VSTFQTSPVL SNRGKGSTHY STDSQPQTTQ AALLQRPPSR VSPENPTEKG RGRPGKSPER
SHVSSEPYEP ISPPQAPANL EKQESVVQPP QRREAEPTEQ RLPPSNEWLP MPLLVRRGRA
PDSATRSEAR SPGNVGYLPA FFTKLENTSP MVKSKKQEIF RKLNSSGGGD SDIANAQPGT
EIFNLPAVTS SGVVSYKKGS VSSRSHSFAD PASNLGLEDI IRKALMGKYD DKGEDHQVVL
SHPVSASQGN MSTSIPVSSD ARNEEANPSP PSGSTAFPYN PLTMRMMSVA PTSIACAPPA
MGQASSHPPA RTWEREPAPL LSSQYETLSD SDD
//
