ID A0A401UQ79_9CLOT Unreviewed; 1397 AA.
AC A0A401UQ79;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GCD11713.1};
GN ORFNames=Ctaglu_33360 {ECO:0000313|EMBL:GCD11713.1};
OS Clostridium tagluense.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=360422 {ECO:0000313|EMBL:GCD11713.1, ECO:0000313|Proteomes:UP000287872};
RN [1] {ECO:0000313|EMBL:GCD11713.1, ECO:0000313|Proteomes:UP000287872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A121 {ECO:0000313|EMBL:GCD11713.1,
RC ECO:0000313|Proteomes:UP000287872};
RA Murakami T., Segawa T., Shcherbakova V.A., Mori H., Yoshimura Y.;
RT "Genome sequencing and assembly of Clostridium tagluense strain A121.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCD11713.1}.
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DR EMBL; BHYK01000021; GCD11713.1; -; Genomic_DNA.
DR OrthoDB; 9803237at2; -.
DR Proteomes; UP000287872; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 2.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR InterPro; IPR040982; DNA_pol3_finger.
DR InterPro; IPR004805; DnaE2/DnaE/PolC.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR006142; INTEIN.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR004042; Intein_endonuc.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR NCBIfam; TIGR01443; intein_Cterm; 1.
DR PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR Pfam; PF07733; DNA_pol3_alpha; 1.
DR Pfam; PF17657; DNA_pol3_finger; 1.
DR Pfam; PF02811; PHP; 1.
DR PRINTS; PR00379; INTEIN.
DR SMART; SM00305; HintC; 1.
DR SMART; SM00306; HintN; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 4: Predicted;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Protein splicing {ECO:0000256|ARBA:ARBA00023000};
KW Reference proteome {ECO:0000313|Proteomes:UP000287872};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 642..773
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT DOMAIN 844..866
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
SQ SEQUENCE 1397 AA; 162932 MW; F4449E9BC7161AE5 CRC64;
MEKIYQNYHK HTSYSNVYTK DSPLVTNDYL VKMKEIGGKQ IYSTVEHGFQ SPYFRVYDEL
EEFNRANETD IKFIFGAEVY WVKDRLSTDR SNCHMVLLAR NEKGRKALNK AISIANKTGY
YYKPRLDLEL ILGLPKDDVF VTTACLAFWN KYEDMNEVVL KLNEHFTHFY LEVQSNHTER
QVEVNKNILA LSVMYNIPLI AGTDSHVIDN SQLADRDDLL KSSGIAYPEE DGWFMDFPSY
DTFYNRFVEQ GVLSEEQITK AIDNTNIILD FDDIILNRTM KMPTLYPNLN QTEKDKIFIQ
TIFELWDKEK EKIPQELHKQ YTDEIVKEMN EILGCAMCDY FLFNKKVIEL GIEKYGGELT
QSGRGSNVAM YLNKLLGFTN IDCISAPIDM YSERFLTKER VLESKTPPDE DYNVTDRIPF
LLAQKEILGD DRCYDLISFG RLHLKSAFKM YARANDVDAQ VANDVSKQIE KYEKAVLYAE
DDEKDDIDMY DYIDKEEFGH IIEGCQRYLG IVDNRKSHPC FTKNELITTD KGYKKIKAIV
LGDKVLTHNN KFEKVMKLMD RESNDIYNLK AMGSLGIEVT GNHPMLVGRR IKPKNKMDLK
VDWIPVSELK KQDMMAVAIN NNSIIPCNDF DLPFDNKDFW WIIGRFIGDG WYEEFARLSG
KCEGDIVKRT IICCGKGKNE LEDIKSKIGN MFEYRVQEET TTYKIIIKGK DIHEYVKTFG
KYAYGKRFTN DILDLPIELL KVFLEGYFSA DGHLTKKGYQ SLKTVSKELA LGVVACVNKA
YHMPCGITYI APKVEYIEGR KVNSKEKYDV KFKYVVCKKD RAFYKDGYIW CPYYSKEKLD
KTDTVYNIEV ENDHSYTVNN LVVHNCGSIV ASCDIEEEVG IVLCKSETTK KEVLTALIES
ITIDAFGWLK NDFLIVDSTR IINSVYRRIG MQPIEINDLL KIIKDDKKVW DIYANGHTQC
INQCEKEKTT QKMMIYKARN IVELTQFIAG IRPSFKSLYS YFEKRQRYQY NIKALDTLLQ
NQYCDSSFIL FQEDLMKILA FAGFAMKDTY NIIKAISKKK KKKIADVKPK FIATFAQKII
ETGDADNEED ALILAQKVWG IVEDFSSYGF NSPHGFSYAI DSVTQAWQKA NYPYEFYEVV
LQRFTDKGEK TKVSLIKKEM IHFNINLKPM KFRDDNRGFT AYKEKGYITQ PLNSVKNMSK
DAPQILYDMK DIELESFVDL LSHMMCNTKL NKKHIEILIK LDYFSEYGDI NYLLGIYTKH
QELYKKTYVE KTKIKRTIEI KEFIETLTKH TTSIIDRIKF EIELVGYTDL KDSSFDEKLV
MVTNLEFNQY GTPFVTLYNI SVGSTLYIKV NKTNYNKKPF EINDMLYLVL IKNDKKFWIK
DRDEYENVLH NYRMVVE
//
