ID A0A401UQN7_9CLOT Unreviewed; 467 AA.
AC A0A401UQN7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 28-JUN-2023, entry version 13.
DE SubName: Full=Heavy metal-binding domain-containing protein {ECO:0000313|EMBL:GCD11855.1};
GN ORFNames=Ctaglu_34780 {ECO:0000313|EMBL:GCD11855.1};
OS Clostridium tagluense.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=360422 {ECO:0000313|EMBL:GCD11855.1, ECO:0000313|Proteomes:UP000287872};
RN [1] {ECO:0000313|EMBL:GCD11855.1, ECO:0000313|Proteomes:UP000287872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A121 {ECO:0000313|EMBL:GCD11855.1,
RC ECO:0000313|Proteomes:UP000287872};
RA Murakami T., Segawa T., Shcherbakova V.A., Mori H., Yoshimura Y.;
RT "Genome sequencing and assembly of Clostridium tagluense strain A121.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCD11855.1}.
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DR EMBL; BHYK01000022; GCD11855.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401UQN7; -.
DR OrthoDB; 9800141at2; -.
DR Proteomes; UP000287872; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00371; HMA; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 1.
DR InterPro; IPR008972; Cupredoxin.
DR InterPro; IPR028096; EfeO_Cupredoxin.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR039447; UreH-like_TM_dom.
DR PANTHER; PTHR42208; HEAVY METAL TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR42208:SF1; HEAVY METAL TRANSPORTER-RELATED; 1.
DR Pfam; PF13473; Cupredoxin_1; 1.
DR Pfam; PF13386; DsbD_2; 1.
DR Pfam; PF00403; HMA; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS01047; HMA_1; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000287872};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..70
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT REGION 440..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 467 AA; 49267 MW; BA1A446DC75D124C CRC64;
MSVKKEKIKV FDMTCTSCES RVERAVRKLD GVKTAKASFS DQSLTIEYDT DFCNNEKIKT
TIKAAGYSTE NSNNYRIVGI FIIVAAIILI GNSTGGIDMT SKLNGATYFV LFIVGAITSI
HCVGMCGGIM LSQSINKDSK SKFDSMKPAI LYNAGRVVSY TILGGIVGSL GSVLSLSLPV
KAGLQIFAGL FMIMMGLNMS GYSLFRKFNI KLPWSACKVK KKPKTPFLVG AFNGLMPCGP
LQTMQLYALG TGSAYKGALA MLIFSLGTVP LMLTFGAVSG LISKGYTKTL LKFSGILVVV
LGMVMGTRGL ALAGVNVPST ASLAATLSGN KTSASATPAA KPIIENGVQI VRMTADGAGY
TPNGLYIQKN MPVKWIIDGK ALNSCNSQII IPSLNIEKNL EPGENVIEFT PKDQDINFSC
GMGMIRGVFK VVDNVKAVDT SKPDASIPAP SSGMPGCNMG GGDSTAP
//
