ID   A0A401Y303_9ACTN        Unreviewed;       786 AA.
AC   A0A401Y303;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE   AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN   ORFNames=NLS1_10170 {ECO:0000313|EMBL:GCD89011.1};
OS   Nocardioides sp. LS1.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=1027620 {ECO:0000313|EMBL:GCD89011.1, ECO:0000313|Proteomes:UP000288271};
RN   [1] {ECO:0000313|EMBL:GCD89011.1, ECO:0000313|Proteomes:UP000288271}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LS1 {ECO:0000313|EMBL:GCD89011.1,
RC   ECO:0000313|Proteomes:UP000288271};
RA   Morimura H., Sato I., Uesaka K.;
RT   "Draft Genome sequence of the deoxynivalenol-degrading actinomycete
RT   Nocardioides sp. strain LS1, isolated from wheat leaves in Japan.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC       {ECO:0000256|ARBA:ARBA00038000}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GCD89011.1}.
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DR   EMBL; BIFF01000002; GCD89011.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A401Y303; -.
DR   OrthoDB; 9809851at2; -.
DR   Proteomes; UP000288271; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR   Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041552; UvrA_DNA-bd.
DR   PANTHER; PTHR43152:SF2; DRUG RESISTANCE ABC TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF17755; UvrA_DNA-bind; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:GCD89011.1};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000288271};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          8..466
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   DOMAIN          480..775
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
SQ   SEQUENCE   786 AA;  83515 MW;  B0BF3AA88C379856 CRC64;
     MSPQSTPADS HDLIRVQGAR ENNLKDISLE IPKRRLTAFT GVSGSGKSSL VFATIAAESQ
     RLINETYSAF LQGFMPSLAR PEVDYLDGLT TAIIVDQERM GANPRSTVGT VTDANAMLRI
     LFSRIGSPHI GPPTAFAFNV PTRVASGMMK TDKGQGSTSV VRNAVYQGGM CPKCEGMGAL
     NDFDLTAIYD ESKSLSEGAL LVPGYSMDGW YGRIFSGAGL DMDKPIAKYS ARDLKKLLYG
     EPEKIKVDGV NLTYEGVLTK VQKSMLSKDV ESMQPHVRRF VERAVTFTTC PDCDGTRLSA
     EARSSKIRGR NIAELCAMQI TDLGEWLREL DEPSVAPLLA GLRHLIDAFT EIGLGYLSLD
     RPSGTLSGGE AQRTKMIRHL GSSLTDVTYV FDEPTIGLHP HDIERMNQLL LQLRDKGNTV
     LVVEHKPETI AIADHVVDLG PGAGTAGGSI CFEGTVEGLA GSDTTTGRHL HDRASLKESL
     RTATGTLEVR GANTHNLRDV DVDLPLGVLC VVTGVAGSGK SSLIHGSVAQ REGVVVVDQG
     AIKGSRRSNP ATYTGLLEPI RKAYAKANGV KPALFSSNSE GACPACNGAG VIFTELGVMA
     TVESLCEECE GRRFQASVLE YTLGGRNIAE VLAMPVVEAL DFFGDGDAAT PAAHKVLERL
     ADVGLGYLTL GQPLTTLSGG ERQRLKLAVQ MADKGDVYVL DEPTTGLHLA DVENLLGLLD
     RLVESGKSVV VIEHHQAVMA HADWIIDLGP GAGHDGGLVV FEGTPAALVA DGSTLTGQHL
     AAYVGG
//