ID A0A401Y8Y6_9ACTN Unreviewed; 428 AA.
AC A0A401Y8Y6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Crotonyl-CoA carboxylase/reductase {ECO:0000313|EMBL:GCD91117.1};
GN Name=adhP {ECO:0000313|EMBL:GCD91117.1};
GN ORFNames=NLS1_31230 {ECO:0000313|EMBL:GCD91117.1};
OS Nocardioides sp. LS1.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1027620 {ECO:0000313|EMBL:GCD91117.1, ECO:0000313|Proteomes:UP000288271};
RN [1] {ECO:0000313|EMBL:GCD91117.1, ECO:0000313|Proteomes:UP000288271}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS1 {ECO:0000313|EMBL:GCD91117.1,
RC ECO:0000313|Proteomes:UP000288271};
RA Morimura H., Sato I., Uesaka K.;
RT "Draft Genome sequence of the deoxynivalenol-degrading actinomycete
RT Nocardioides sp. strain LS1, isolated from wheat leaves in Japan.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCD91117.1}.
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DR EMBL; BIFF01000005; GCD91117.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A401Y8Y6; -.
DR OrthoDB; 9790818at2; -.
DR Proteomes; UP000288271; Unassembled WGS sequence.
DR GO; GO:0043880; F:crotonyl-CoA reductase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08246; crotonyl_coA_red; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR010085; Crot_CoA_red.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR NCBIfam; TIGR01751; crot-CoA-red; 1.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000288271};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 46..410
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 45438 MW; AD397D9629181F72 CRC64;
MASSHQAERN SVVTPGVEPT PVGQLPPVGQ VPSHMHAQLV RQDRFGDPAT AFVAEVVPTP
DIRPDEVLIG VMAAGINYNN VWAARGYPVD QIATRQRRGE TEDFHIGGSD ASGIVYAVGG
EVNGIEVGDH VVTHPGVWDA DDAWIARGKD QMTAPTARIY GYDTNYGSFG QFTRVQAHQV
LPKAAHLTWE EAAAPTLVGT TAYRMLHGWQ GNVVSEGDVV LVWGGSGGLG SQAIQLARLA
GAIPVAVVSE PERGAYAEKL GAAGWINRRD FNHWGVPPLV DDAAGQKAWT AEARTFGKRI
WDIVGSRQDP AIVFEHPGAA TIPTSIFVCE TGGMVVICAG TTGYDAMVDL RYHWTRQKRL
QGSHGTNDAE ARAYNDLVLA GAIDPALGRT IRFEDIPGAH AAMGRGEEVF GNVSALVGAP
HPGAGADL
//
