ID A0A402B2Z4_9CHLR Unreviewed; 878 AA.
AC A0A402B2Z4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=KDA_11770 {ECO:0000313|EMBL:GCE25693.1};
OS Dictyobacter alpinus.
OC Bacteria; Chloroflexota; Ktedonobacteria; Ktedonobacterales;
OC Dictyobacteraceae; Dictyobacter.
OX NCBI_TaxID=2014873 {ECO:0000313|EMBL:GCE25693.1, ECO:0000313|Proteomes:UP000287171};
RN [1] {ECO:0000313|Proteomes:UP000287171}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Uno16 {ECO:0000313|Proteomes:UP000287171};
RA Wang C.M., Zheng Y., Sakai Y., Toyoda A., Minakuchi Y., Abe K., Yokota A.,
RA Yabe S.;
RT "Tengunoibacter tsumagoiensis gen. nov., sp. nov., Dictyobacter kobayashii
RT sp. nov., D. alpinus sp. nov., and D. joshuensis sp. nov. and description
RT of Dictyobacteraceae fam. nov. within the order Ktedonobacterales isolated
RT from Tengu-no-mugimeshi.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCE25693.1}.
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DR EMBL; BIFT01000001; GCE25693.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A402B2Z4; -.
DR OrthoDB; 9814968at2; -.
DR Proteomes; UP000287171; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR018764; Anti-sigma_K_RskA.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR43671:SF13; LD04361P; 1.
DR PANTHER; PTHR43671; SERINE/THREONINE-PROTEIN KINASE NEK; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF10099; RskA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287171};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 515..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..291
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 371..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 841..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 845..860
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 878 AA; 94389 MW; DFFA07E0F7D271EE CRC64;
MSTSPRRIGQ YELLQQIGNG HVGEVWKAHD LAQRRDVAVK ILHNDLQADP NFLNRLTNGG
KAITNLRHDN LVSVYDARVS RPNEARETTT FIVMDYIEGY TISDYLKATA QRGIFPATTD
IVYLFSCLGA VVDYIHQQGI AHGDIKPSNI LLNKQQRTRF NAGEPMLTDV GITQIAGNDS
YLGAPHYLSP EQAQGQSAKK ESDIYALGII LYELCTGATP FRGDNSFAVI SQHINTLPTP
PTLLNANIPP DLAQVILRAL SKDPGARFSE GAQFAYAIAE ACSVQPTHPA VRQIATRSQQ
AQTSSNPAQN NQQSILGVSQ PLTPASPVFM RPLIDMATRQ QSQAGQEQPI SLNANPNVSA
AAVFPNSGPL SSVTIQKNPG PASLPSTAPA SGFPQSGPAS VPPSGATSGP LSGASGKQFQ
LRQTSLTRIP VVGPDKPGLQ FSLPSTPSSP DLSATQQSQV RPDYVQAEPV RPYPQQPDPA
AYRAYQQQAA PQIPQTPPPL AVPPPTRPAV YKNKYFILIA ALVLIAVIAA SIGLSNALKP
NDKAGQPAPA VTTKNPLPTP QGPGIVFFQD DALGRNDQLR ITMKDIPDPA QGKVYYAWLQ
TNTQKFVPLG AMQAQNKQID FMYAGDANHT NLINYTSGIQ ITLEDTGNNP TTPGKKVVYR
AAFAQATLPE IQNILDSTPG LPKGQSAVSN MFETIKSLND KAASIVDSLD QTKDYGLVKR
QATRIIELID GSNYARSSGD LPNTLPGQIK TPIGLLSSPN QPGYIDILDK HLDALKANAG
NNANLQMRIQ NAKAGLTDLR QWLQKMRDND VQLLKATNLT DAKNHAAALQ LKQLADYSYK
GRTIPPDTSP KSTPGSAGAS QTYVETQYMA ALDLTAVK
//
