ID A0A402BM62_9FIRM Unreviewed; 785 AA.
AC A0A402BM62;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 13-SEP-2023, entry version 10.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:GCE32414.1};
GN ORFNames=SPFL3102_00189 {ECO:0000313|EMBL:GCE32414.1};
OS Sporomusaceae bacterium.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae.
OX NCBI_TaxID=1917525 {ECO:0000313|EMBL:GCE32414.1, ECO:0000313|Proteomes:UP000287175};
RN [1] {ECO:0000313|EMBL:GCE32414.1, ECO:0000313|Proteomes:UP000287175}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FL31 {ECO:0000313|EMBL:GCE32414.1,
RC ECO:0000313|Proteomes:UP000287175};
RA Aoyagi T., Kurasawa H., Amachi S., Nakajima N., Hori T., Yamamura S.;
RT "Draft genome sequence of Sporomusaceae bacterium strain FL31, a lactate-
RT fermenting bacterium of the class Negativicutes.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCE32414.1}.
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DR EMBL; BIFV01000002; GCE32414.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A402BM62; -.
DR Proteomes; UP000287175; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287175};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 539..738
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 785 AA; 84464 MW; 4DA50F1F8B467791 CRC64;
MVFINYITMA IVLGIWLAGH VGVAVFWWNL LIVIFFACSL WGIRKNFSKV RWIIVILFVF
VGAVRFVHDQ APAPNMISRY TGQILAIQGT ICEIPQTFVI DKGQLRARYV VSAEHIGVSD
GRGFIGEGKV IVTTHQERER KIGEIGDHIT VRGELSDLHG FNNPGLIDTV AALKRVGIVG
RMSVSSEHIQ IDSASDKSWF NKVALLKEKV ALMLKRELPP AESAILFGML FGGYSGIAAD
VIAAFSATGI VHILSVSGTH IALVAGVIYW VCSFLKIKGK NAAGLVIVVV LSYGVFVGFT
PPVIRSAVMG IVAVGAIALG RERDSYHALA ITTVGMLMAQ PSLIYDISFQ LSFGSTAGLI
YLFPKIKSSI TFLPVWMAAP IAMTLAAQLG VLPFVSWYFN VFSLSSFAAN LVIVPIVELV
VVLGLAGVLT GFLLNFLSHL ILAFCSVMIK GVVYLTKLLA GIPGGTIYLP SFDIVTGLLY
YVILGWLFGF SLPGMASVRS GIQRWPRQVI GLAAILLVVG GWYICGPKPA AIHFIDVAQG
DATLIVSPHG RAVLVDTGGT TGQTDFDIGE RVVTPYLKHY GVRSLDYLIL THGHQDHAGG
AAAVSKHIPI KHILVAREPY SAAVQQLQAA AEDAVFIPAY IGQQIQLDGL VIQIVYAADS
KLAKASNEAS NVIKISYGDH SFLITGDLES QGETAILLDQ SLVASTVLKV GHHGAKTSSS
LEFLQEVSPA YAVISVGAGN RFGHPHPEIL KRLSDRQIKV FRTDLQGAIV FETDGKSLNA
KSFIP
//
