ID A0A402BSL5_9FIRM Unreviewed; 710 AA.
AC A0A402BSL5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SPFL3102_02118 {ECO:0000313|EMBL:GCE34307.1};
OS Sporomusaceae bacterium.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae.
OX NCBI_TaxID=1917525 {ECO:0000313|EMBL:GCE34307.1, ECO:0000313|Proteomes:UP000287175};
RN [1] {ECO:0000313|EMBL:GCE34307.1, ECO:0000313|Proteomes:UP000287175}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FL31 {ECO:0000313|EMBL:GCE34307.1,
RC ECO:0000313|Proteomes:UP000287175};
RA Aoyagi T., Kurasawa H., Amachi S., Nakajima N., Hori T., Yamamura S.;
RT "Draft genome sequence of Sporomusaceae bacterium strain FL31, a lactate-
RT fermenting bacterium of the class Negativicutes.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GCE34307.1}.
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DR EMBL; BIFV01000008; GCE34307.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A402BSL5; -.
DR OrthoDB; 1671731at2; -.
DR Proteomes; UP000287175; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF34; SPORULATION KINASE A; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000287175};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 369..439
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 439..493
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 506..710
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 710 AA; 80964 MW; 9BA550ADAB2843B4 CRC64;
MNSSVLAQKT CILATMIITI PMILFGWMNA NNSRDRIIAE KEQMLLRIAA SLELRFPDSY
EGILKHSPQS ANEQEKLLLL HKRLQPIIDE VAQRYPEYGM GYGMSTQRIA YYPYRQELFN
RPISQWVLNA YDKQEFLLQR RAMSPTWGQP TMSLIYPLCF NGKMIGHIWV NAKLGDINQA
IYFAWAQNLV ILIITWLGLI FLLQKAFNSI GQELKAFSAS IEEKTDNFEQ LTTLPELQPL
RAAVIGLREG LEQEKDAVQN ALLAVHQTLD RITDFFFALD REFRFIYINS KMAEMYRSVV
VGQRIWDALP ASRGFAAQFE QALAEQISVC YTAFSPTILK WLEISIYPSP HGLTVYMKDI
HDQRLAQNQI KEQARLIDLV QDPIMMWDME GTVIFWNGGA EKSYGWSKAE ALGQNILDLI
QTQFPQSLDK HMQELLEHGY WEGELVDSCK DGRRVVVKSH WTINKDVSGK VAAVFAINRD
ITEKRKIEEE LARFDSLHTL GEMAAGIGHE VRNPLTTVRG YLQVFSYKGK FREYQEQFHT
MIEELDRANS IITEFLSLAK NKSLDMECCN LNDIIRPLFP LLQADGFRLG HDVQLELTDI
PNSCFDQKEI RQLILNLVRN GFEAMTSAGQ VTIRTYAEPG AIVLVIRDTG TGIPAEMLDK
LGTPFLTTKE SGTGLGLPVC YRVAERHAAQ IAIDTSAQGT TFYVKFNHSK
//
