ID A0A409VA46_9AGAR Unreviewed; 684 AA.
AC A0A409VA46;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Beta-trefoil DNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=CVT24_004283 {ECO:0000313|EMBL:PPQ63703.1};
OS Panaeolus cyanescens.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Galeropsidaceae; Panaeolus.
OX NCBI_TaxID=181874 {ECO:0000313|EMBL:PPQ63703.1, ECO:0000313|Proteomes:UP000284842};
RN [1] {ECO:0000313|EMBL:PPQ63703.1, ECO:0000313|Proteomes:UP000284842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2629 {ECO:0000313|EMBL:PPQ63703.1,
RC ECO:0000313|Proteomes:UP000284842};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Su(H) family.
CC {ECO:0000256|ARBA:ARBA00009704}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ63703.1}.
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DR EMBL; NHTK01006113; PPQ63703.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409VA46; -.
DR STRING; 181874.A0A409VA46; -.
DR InParanoid; A0A409VA46; -.
DR OrthoDB; 1384914at2759; -.
DR Proteomes; UP000284842; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.60.40.1450; LAG1, DNA binding domain; 1.
DR InterPro; IPR015350; Beta-trefoil_DNA-bd_dom.
DR InterPro; IPR036358; BTD_sf.
DR InterPro; IPR040159; CLS_fam.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR015351; RBP-J/Cbf11/Cbf12_DNA-bd.
DR InterPro; IPR037095; RBP-J/Cbf11_DNA-bd_sf.
DR PANTHER; PTHR10665; RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS; 1.
DR PANTHER; PTHR10665:SF0; SUPPRESSOR OF HAIRLESS PROTEIN; 1.
DR Pfam; PF09270; BTD; 1.
DR Pfam; PF09271; LAG1-DNAbind; 2.
DR SMART; SM01268; BTD; 1.
DR SMART; SM01267; LAG1_DNAbind; 1.
DR SUPFAM; SSF110217; DNA-binding protein LAG-1 (CSL); 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000284842};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 114..247
FT /note="RBP-J/Cbf11/Cbf12 DNA binding"
FT /evidence="ECO:0000259|SMART:SM01267"
FT DOMAIN 248..425
FT /note="Beta-trefoil DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01268"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 577..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PPQ63703.1"
SQ SEQUENCE 684 AA; 72698 MW; 4C69BE4953203BEC CRC64;
PSTASPQPDQ PSLPANNSHT PSSSSSAAPS PSIPTADPNV SIQSILKDAA NGQATQPWPA
PGQPVAIAPN VHHQPSSSKR KLEDEETDDP HTKIRRIVRD HVSSDPSRVM PMTTVICLHA
AVAQKSYGSE KRFLCPPPVV HIDGPVWHMR SQQLAMAVVS ETGDRSFEQK APLDNNMTAS
FKFLHVTGTA KAKSFQLSLD IAEPPLPGVV GDGTEPPSGR VWASFDSAPV TIISKPSKKT
AKTRNISSCI LAGGPVSLFN RINSQTVRTK YMTIDHAQLC ASNVAWSAFN VNVVRKPGPP
PPTVAGPQPV TYGCEIILSD THSGISTAPL IIRKVDKGKV THDEGGPVSQ MQKIALQRVN
PDGTRHYLSA AGPMPGNPGV IAPPAPGISS QAGTHPLVFQ APRVREEIKD GYRVVCDEVD
DYLCWTIVGI SKFQYTFFDA FGQNNTIPEM PITPFPTLFT APVYRPANNT IELTVSNFFY
DHPTTRVQTP LDVYLGNLGP LPLRVYQATP PGPLTAINPF LPPAPGAQVM DPQNPVGSPQ
MGHRFMPSHT VVIVEMPPLA DVIKALEDDA LPLSMERKSP IGEDANGGES SSASASGAPP
PQPSLANIAG RSLPLLFIRS SDGVGYHSGR TIACDNVFTN MELGGLAASQ ANGQPGNLDT
GWLQAAQAAA AADGGMHGWT LRVM
//
