ID A0A409VFS2_9AGAR Unreviewed; 1637 AA.
AC A0A409VFS2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CVT24_003061 {ECO:0000313|EMBL:PPQ65100.1};
OS Panaeolus cyanescens.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Galeropsidaceae; Panaeolus.
OX NCBI_TaxID=181874 {ECO:0000313|EMBL:PPQ65100.1, ECO:0000313|Proteomes:UP000284842};
RN [1] {ECO:0000313|EMBL:PPQ65100.1, ECO:0000313|Proteomes:UP000284842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2629 {ECO:0000313|EMBL:PPQ65100.1,
RC ECO:0000313|Proteomes:UP000284842};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ65100.1}.
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DR EMBL; NHTK01006076; PPQ65100.1; -; Genomic_DNA.
DR STRING; 181874.A0A409VFS2; -.
DR InParanoid; A0A409VFS2; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000284842; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd15480; fMyo2p_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR046943; Fungal_Myo2/2A_CBD.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140:SF860; DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 5.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000284842}.
FT DOMAIN 75..817
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1307..1586
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 627..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..714
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1153..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 983..1076
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 629..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1155..1175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1637 AA; 185012 MW; D6F2BB65744127C6 CRC64;
MAENIYSKGT KVWFEDKDQA WIPAEVSSVT KGNDDSIKLV FIDERGKETI INTTGKEIKE
GKEGLPPLRN PPLLETADDL ATLSHLNEPS VLHAIRNRYI QHSIYTYSGI VLIAVNPFQR
VTLYGPEIIA AYSGRKRGEL EPHLFAIAED AYTAMRKDGT GQTIIVSGES GAGKTESAKF
IMRYLASVNP PDSSSKSSKP KFSLDESSEI ERQILATNPI LEAFGNAKTT RNDNSSRFGK
YIQILFDGKQ EIVGARIRTY LLERSRIVFQ PLTERNYHIF YQLCAGAPLK ERKDLGLDPD
INKFFYLKQG GPSSTPINGV DDAEEFRSTQ QALSTVGISV EKQWAVFRLL AALLHLGNVK
IIPGRTEASI DDNDPALLLA TRFLGVNLAD FKKWTVKKQI QTRSEKIVTS LNAAQATVVR
DSVAKFVYAC MFEWLVAIVN ESLAGENGDA AERAEMFIGV LDIYGFEHFQ KNSFEQFSIN
YANEKLQQEF NSHVFKLEQE EYVKEEIKWK FIDFSDNQIC IDVIEGKLGV LALLDEESRM
PSGTDPSFLQ KLNAQILGKP EYKDVFKKPR FGNTSFTIAH YALDVTYEVE GFLEKNRDTV
PDEHMALLAS TKNTFLKEVL DAALNSTRGV EPATPSSPAI SDSGSGGSRR SSVIPDPGRT
SFVAQSTGGG APKRPGAANK KPTQGSIFKA SLITLMETLS TTNVHYIRCI KPNEQKRPFE
FHPQQVLGQL RACGVLETIR ISCAGYPTRW TYEEFAERYY MLVPSSVWQP LIQSMDLRTL
CSAVLDKTIA DTDMYQNGLT KIFFRAGMLA ALESLRSERL NKMVTVVQKN VRRQLAMKRY
QKLRKATIKI QTWWRGIMAK RLVENIRREV SAIRIQTAVR AFIQRKNFLA VRHSVILVQN
RIRGMQARQR FVQDRITSAA TLLQSLFRGV LSRRNFRADV RHVVFIQSSI RRRLAKKQLK
VLKAEARSVS KFKEISYRLE NKVVELTQSL QERTVEKKKL QAQLSEVEQQ LQQWINRHEE
ADSRAKQLQG NMQAMEAELA QRNELLASKV DLEKRLDDAH AKLAEKEALI TKLTEDVIKQ
AATLEAQQRA IDATPSRNHE DSSVIMTLKN EVSSLREQLN RSNALNALTR GGPRMEPPLS
PTFAPALRLA NEANGHVNGN GSISSNQTRG HQRRHSSAGV FSLAGLENRN SADDLMNDVK
RNHAANPRAV SVAFNGEDNY LRFRNSGLPE IRDYDDPAEE KIRLMQDVKR LDEDVLDGLI
RGLKIPAPSL TNPSAVKEIL FPANLISLVT NEMWKYGLIP ESERFLANVM QTIQAHVMSF
SGEDAIVPGI FWLSNVHEML SFICVAESDM LQGIGPGEDN AVRPFDWNDY ERLVSVVKHD
LDSLEYNIYH TWMLETKKRL AKMVIPALIE SQSLPGFTTS EGTRLFNRLL NTNSQPAHSM
DDILNLLNKV WKSLKSYFME ESVVHQVITE LLKLIGVTSF NDLLMRRNFS SWKRAMQIQY
NITRIEEWCK SRDMPEGALQ LEHLMQATKL LQLKKATPAD IEIIYDVCWM LTPMQIQRMC
TNYYVADYEN PISPEILRVV ASRVQANDKN DHLLLPPETE EVGSYEIPLP REVSGLETYV
PAYLNVSHLR RLAALVA
//
