ID A0A409VLC5_9AGAR Unreviewed; 760 AA.
AC A0A409VLC5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=CVT26_009930 {ECO:0000313|EMBL:PPQ67033.1};
OS Gymnopilus dilepis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Gymnopilus.
OX NCBI_TaxID=231916 {ECO:0000313|EMBL:PPQ67033.1, ECO:0000313|Proteomes:UP000284706};
RN [1] {ECO:0000313|EMBL:PPQ67033.1, ECO:0000313|Proteomes:UP000284706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRW20 {ECO:0000313|EMBL:PPQ67033.1,
RC ECO:0000313|Proteomes:UP000284706};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ67033.1}.
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DR EMBL; NHYE01005615; PPQ67033.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409VLC5; -.
DR STRING; 231916.A0A409VLC5; -.
DR InParanoid; A0A409VLC5; -.
DR OrthoDB; 9585at2759; -.
DR Proteomes; UP000284706; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.1690.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011546; Pept_M41_FtsH_extracell.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR43655; ATP-DEPENDENT PROTEASE; 1.
DR PANTHER; PTHR43655:SF2; SD01613P; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF06480; FtsH_ext; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000284706}.
FT DOMAIN 292..432
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..743
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 83594 MW; 36CA56C08D1C2C42 CRC64;
MLSRSLRAAA RLRPRSVPIA AVRAFATPSP KKEGQSDNKP SKPELPKALE GFFKQYKESQ
RRQPSSDQKS SSENQSGGRR DRKDQQQPPP PQQNGFNQQQ LAWIVASATA YLLWSSSSAH
NSKEITWQEF RANFLDKGLV ESLTVVNKHH VRVKLHPNAS GTNPGEFYFT IGSVDAFERK
IDDAQTELGI PSSERIPVSY VDEISSVGAL LNFAPTLLLI GVLYWISRRG SSGSAGGIFN
IGKSRAKLFN HESEVKVKFS DVAGMDEAKE EIMEFVKFLK EPAKYEKLGA KIPRGAILSG
PPGTGKTLLA KATAGEASVP FLSVSGSEFV EMFVGVGSSR VRDLFASAKK NAPCIIFIDE
IDAIGKARGK GGSFGGNDER ESTLNQLLVE MDGFGTNEHI VVLAGTNRPD VLDPALMRPG
RFDRHIAIDR PDVSGRKGIY LVHLKPIRLE DSLKSDLESF AQKLAVLTPG FSGADIANVC
NEAALHAARR GSDYVEQVDF DTAIERVIVG LEKKSRVLSP EEKKTVAYHE AGHAICGWFL
EHADPLLKVS IIPRGAGALG YAQYLPADRY LLSTPQMMDR ICMTLGGRVS EEIFFGAENI
TTGAQDDLQK ITRMAFEACA NYGMNDVIGP VSYGGDRAAK ESWTKPFSEK TAEMLDFEVR
KMITTAYSRT RDLLTLHKEN VEKVAKRLLE KEVITREDMI ELLGKRPFAG RADDMDKWLD
ENRGEKSAPP PLESPPQSDV DDPLPQPAPM TKSLDDRSLL
//
