ID   A0A409VQ79_PSICY        Unreviewed;       540 AA.
AC   A0A409VQ79;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=CVT25_007927 {ECO:0000313|EMBL:PPQ68389.1};
OS   Psilocybe cyanescens.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX   NCBI_TaxID=93625 {ECO:0000313|EMBL:PPQ68389.1, ECO:0000313|Proteomes:UP000283269};
RN   [1] {ECO:0000313|EMBL:PPQ68389.1, ECO:0000313|Proteomes:UP000283269}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2631 {ECO:0000313|EMBL:PPQ68389.1,
RC   ECO:0000313|Proteomes:UP000283269};
RX   PubMed=30283667; DOI=10.1002/evl3.42;
RA   Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA   Matheny P.B., Slot J.C.;
RT   "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT   diversity.";
RL   Evol. Lett. 2:88-101(2018).
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPQ68389.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NHYD01003958; PPQ68389.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A409VQ79; -.
DR   STRING; 93625.A0A409VQ79; -.
DR   InParanoid; A0A409VQ79; -.
DR   OrthoDB; 1552062at2759; -.
DR   Proteomes; UP000283269; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR   PANTHER; PTHR43142:SF1; CARBOXYLIC ESTER HYDROLASE; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283269}.
FT   DOMAIN          19..279
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   540 AA;  59898 MW;  6F417B9372315EA1 CRC64;
     MSGVPHLHDE LVNNPERVTV ETAFGPVIGG RAKNGSAIFL EVPYALPPGR FEDPVALPAD
     YRYDEHKEYI RETAYAVQPL NDGQAADMPF KDKVGLGEPS ENPLFLNIAI PPTFPKVKGF
     PVRIYIHGGF LQFGSPHSLG SQAQYSAAER SEIWVNVGYR LSAFGFIACD KPMLTGNYGF
     KDQWVALEWI KANIEAFGGN PNDIQITGLS AGGHSVHQLL HHASMLPAGK SAPFNSAVLQ
     SNAMLTDPKT PEELRPQFSA LCQALGLDPD APDVLQTLKD PSKVLWQSIT KAIETDAIGH
     FGTFRGCLSE DWISVNPGPM EWQRCGGLSR GLQTRGVSSI VVGDLTEEWY LYSIAHPING
     PADILPNLER YFPTSIAEGF LKAFPQLPSQ AGAKESTRLY GDIMSCGQVH LPVRLLAKDL
     EAQGYPVMRY EIRWTPEQYR PFGESKGYVT HGCDRLLWAL RIPSLEPDQI EIAKEWVNSV
     SKEVEEMNAG KSCHNSRRML TLKEDKSIGW TSDEKWAELM KLEPILESRR GKYGVPFYNV
//