ID A0A409W450_9AGAR Unreviewed; 1182 AA.
AC A0A409W450;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=NodB homology domain-containing protein {ECO:0000259|PROSITE:PS51677};
GN ORFNames=CVT26_015041 {ECO:0000313|EMBL:PPQ73238.1};
OS Gymnopilus dilepis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Gymnopilus.
OX NCBI_TaxID=231916 {ECO:0000313|EMBL:PPQ73238.1, ECO:0000313|Proteomes:UP000284706};
RN [1] {ECO:0000313|EMBL:PPQ73238.1, ECO:0000313|Proteomes:UP000284706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRW20 {ECO:0000313|EMBL:PPQ73238.1,
RC ECO:0000313|Proteomes:UP000284706};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC {ECO:0000256|ARBA:ARBA00004589}.
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC {ECO:0000256|ARBA:ARBA00009884}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ73238.1}.
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DR EMBL; NHYE01005416; PPQ73238.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409W450; -.
DR STRING; 231916.A0A409W450; -.
DR InParanoid; A0A409W450; -.
DR OrthoDB; 4609640at2759; -.
DR Proteomes; UP000284706; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR GO; GO:0004099; F:chitin deacetylase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.40.60; -; 1.
DR Gene3D; 3.40.50.1910; -; 1.
DR Gene3D; 3.40.50.2060; -; 1.
DR Gene3D; 3.20.20.370; Glycoside hydrolase/deacetylase; 1.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR002509; NODB_dom.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR043127; Sec-1-like_dom3a.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR PANTHER; PTHR11679:SF30; PROTEIN ROP; 1.
DR PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR Pfam; PF01522; Polysacc_deac_1; 1.
DR Pfam; PF00995; Sec1; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
DR SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
DR PROSITE; PS51677; NODB; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00022622};
KW GPI-anchor {ECO:0000256|ARBA:ARBA00022622};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000284706};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 150..358
FT /note="NodB homology"
FT /evidence="ECO:0000259|PROSITE:PS51677"
FT REGION 78..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1004..1033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..98
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1149..1166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1167..1182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1182 AA; 131460 MW; BDB23889C9C825EC CRC64;
MDGSNGRKPV CRVYVGILRV NYLLALVSPA LSLSLLPSLS RYAATDTQIP PLASITMGMP
IRPPPAFTAT YTPGATPPVA GAPALPTASF PPPDQVPDTN SPEVQEWMKE LNGVTIPDIS
QTKDSTCASD PAAAAEAEKR GWWTCGGYTR STDIAACPEK LHWGLRDLIA KLKEKNIKAT
FFVVGSRVIQ RPEILIEEYM NGHEISVHTW SHTPLTTLTN EQIVAELGWT RKAIKDVLGV
TPTTMRPPTG DIDDRVRAIS LAMGMVPVLW SSTADGGKFD SNDWKVASGE ITGSQSFTIF
EDIMRNGTAS NTGFITLQHD LFDVTVDLAV GYTLDAALSH EPKFVLQTVG ECMGMPAGGV
YRETKPSASA RNATLSEATP VGDANVDQGN AKPSVKSSAV DVMTPMLGLI SMDVLSDYHQ
FLEAIRSVNP PSRWKILVVD EHSQRLLGAV LKQFDILEEN VTLIESITSI REPQPEFEAL
YLVMPTTQNV DRIIRDFSNQ KQYAAAHLFF LEGLPEPLFE RLTSSPAEPH LQALKELFLN
FNPIEAQVFS MREPSYFFSM YSPPRTDASF KPARARLEED LWFMSKMIAN VCIALNEFPY
VRYYMPSSHL PLGPLKPNAQ NRPPPPPETA SRWRTNLARG SEARAYEAVE SDFVTKLLAF
RVQQTLEEYK KMNPDFGKPD PARPRATLLI TDRSLDMMAP FVHEFTYQAM ANDLLPIEDG
TKYTSALAID LFSQTADDYS FRYKFQSSVG TYEDKVATLS DADTTYTSVR HLHMREAIDK
LMSDFNKFLE DNAVFNGEGA ANLNDMKDML ASLPQYQEHR EKFSLHLTIA QDCMDIFEKQ
KLSDIASVEQ CCATGLNAEG KTPKGLVEEM VPLLDSREVL NMRKVRVIAL YIQYRDGVPD
EDRRRLYQHA RLTLAEQDAV NALVHMGVRI SRASFFLLSS TSGPKFALIK GPNDKDTKKK
IKQKFAGDEY ELSRFKPILR SVLEDQVGDK LDAISFPYVK DAPMATPLSP RSPPPQTTSL
RSQKPAWHRA PKAATVENRQ RVLVFVAGGV TYSEMREVYN LSNSLHKDIF IGSTHVITPK
GFIDDLKVLD LGGAGSKAIP NGLRDMRGEP KTPQQLYDEK YFVRDEPPPQ RVPARNAPPA
RPERVAAPIQ PSPTNSFQGS VNSMTPSVKD EKKKKRGLFR FG
//
