ID   A0A409W469_9AGAR        Unreviewed;       821 AA.
AC   A0A409W469;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=CVT26_015223 {ECO:0000313|EMBL:PPQ73265.1};
OS   Gymnopilus dilepis.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Gymnopilus.
OX   NCBI_TaxID=231916 {ECO:0000313|EMBL:PPQ73265.1, ECO:0000313|Proteomes:UP000284706};
RN   [1] {ECO:0000313|EMBL:PPQ73265.1, ECO:0000313|Proteomes:UP000284706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SRW20 {ECO:0000313|EMBL:PPQ73265.1,
RC   ECO:0000313|Proteomes:UP000284706};
RX   PubMed=30283667; DOI=10.1002/evl3.42;
RA   Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA   Matheny P.B., Slot J.C.;
RT   "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT   diversity.";
RL   Evol. Lett. 2:88-101(2018).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPQ73265.1}.
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DR   EMBL; NHYE01005414; PPQ73265.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A409W469; -.
DR   STRING; 231916.A0A409W469; -.
DR   InParanoid; A0A409W469; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000284706; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000284706}.
FT   DOMAIN          466..692
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          20..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   821 AA;  93287 MW;  03CAA7ED39139DF1 CRC64;
     MTDVATLLSL PKTSNGLTSI RPTALAGSVD DGSASPPRKV ARLTADSDSA SASRPKLAKT
     AVGPIRIEIV GEYKSKPSQA EVQLGVVRRA IRVFLTRQPG YNDAIPATYE GIYNACRALV
     TVSHRGEDVY NALKMELEQS IGRLSSELLD SDEEDTTWIA SFNAAFKWFE SQISLLKSLL
     TYLDQIYVMQ EKNVLSVRDL AYSLVSDRIF GSAQLVERLR SGVKSWLNWE RENRREHRQR
     EVIPALIAHL VRHHQYSAFE EYYINVTRDF YLEESTKKAR DLKNDPKTFF NHARSRINEE
     AARSKAILPL PSWGILREVT EHALWDGKLE WLADSTLSEY METKDFATLG SMYDLFSRVD
     GIKPLVNAFG NYVRTTVASI VKDADRDDEM VQRLLDFKEL ADDAVSAAFL TDRTTVNTTN
     STQTPGAIPA APVASASTLP PKQPDQQFLY ALTDSFTTGF KARRSKPAEM IAKYLDKAMR
     KGQGKASDAE FQALLDRVLA LYRFTDDKDV FRTFYHRSLA KRLLLGKSAS DDFEKAMLKK
     LKENYDPEFG MGEDMFKDLA LSRESMREYH SRLPEGSPGL KLTAMILQRS AWPFTVQKRT
     VDLPPDMQEE LTKYAEYYKS KHSGHVLDWD HSLGTVTLKA RFKPGMKELS VSMYQALVLL
     LFNEEVEISY TDIKERTRMD EAELKRTLQS LACGKKKVLK KIPVGKDVDD TDVFRFNADF
     HDPHHVVHIN SIQAKVSPEE SKRTNASIED DRKHYLDAAI VRVMKAKKEL AYEQLKAATI
     DAVKNHFVPQ VETIKRRIDA LVEQEYLERS PDDRNKYLYV A
//