ID A0A409W474_9AGAR Unreviewed; 947 AA.
AC A0A409W474;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=CBM1 domain-containing protein {ECO:0000259|PROSITE:PS51164};
GN ORFNames=CVT24_012299 {ECO:0000313|EMBL:PPQ73329.1};
OS Panaeolus cyanescens.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Galeropsidaceae; Panaeolus.
OX NCBI_TaxID=181874 {ECO:0000313|EMBL:PPQ73329.1, ECO:0000313|Proteomes:UP000284842};
RN [1] {ECO:0000313|EMBL:PPQ73329.1, ECO:0000313|Proteomes:UP000284842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2629 {ECO:0000313|EMBL:PPQ73329.1,
RC ECO:0000313|Proteomes:UP000284842};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- PATHWAY: Secondary metabolite biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005179}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ73329.1}.
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DR EMBL; NHTK01005823; PPQ73329.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409W474; -.
DR STRING; 181874.A0A409W474; -.
DR InParanoid; A0A409W474; -.
DR OrthoDB; 2900138at2759; -.
DR Proteomes; UP000284842; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0030248; F:cellulose binding; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd11065; CYP64-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR035971; CBD_sf.
DR InterPro; IPR000254; Cellulose-bd_dom_fun.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR46300:SF1; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR46300; P450, PUTATIVE (EUROFUNG)-RELATED-RELATED; 1.
DR Pfam; PF00734; CBM_1; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SMART; SM00236; fCBD; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF57180; Cellulose-binding domain; 1.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00562; CBM1_1; 1.
DR PROSITE; PS51164; CBM1_2; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 4: Predicted;
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033};
KW Reference proteome {ECO:0000313|Proteomes:UP000284842};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..947
FT /note="CBM1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019354569"
FT DOMAIN 20..56
FT /note="CBM1"
FT /evidence="ECO:0000259|PROSITE:PS51164"
FT REGION 62..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 947 AA; 103177 MW; A15B4A0DA1780E8A CRC64;
MPTAWKPSFV ALLFSLPAFA QQPLWGQCGG IGWTGGTTCV SGAVCNRNND YYSQCIPGQA
TTPAPAPTTS TATTPPPSST SVPAAPGSCP VLPSNPSFTA NARLPNPFKF FNGNAVTTKA
DWDCRREEIS QLLQRYELGT LPPKPSSVTG SYSGGRLTIN VSEAGKSISF QVSISTPSGA
TAPYPAIIAY GGMSIPTPSG VSVITFNNDD IAAQTNTGSR GQGKFYTLYG SGHSAGAMTA
WAWGVSRIID ALSTTTGHNI DLNRIAVTGC SRNGKGALVA GAFDTRIALT IPQESGSGGG
GCWRISDKML SSGINTQTAS EIVGENVWFS KNFEPYVRSI NNLPFDHHLL AALVAPRALL
VIDNTSIDWL GPRSVFGCMK TANKIWQALG VADHMGVSQV GNHNHCAFPS NEQGDLDAFV
NKFLKNQSTN TNIVKTDGAN QVGFVDSEWV DWTTVAVILL CFTLYAYIRQ RVHRGSKLPL
PPGPPGHIIF GNKLPESFAY RKYEEWTQEY GPVFTIRQGF NITIVVGRLQ AAIDIMEKEG
ASLADRPRNI SAGEILSGGM RTLLTPAGER FKKMRRALHT HLQPKVVAGY SPTLMKNAKQ
LLLDIIDAPE RHQDHAKRYS ASVVLALAYG KESQGYEDPA IVAVNRCITR VGENLRPGLW
KVDIYPFLRY IPGYLNELKA GHAEELDLFK TQLREVKVKM ERGDEIPQSF GKYLLEKQQE
LGLNEAETAY LAGSMFGAGS DTTASAISVA ILAAACYPEA QRRIQEEIDA VIGKERAPTT
SDAESLPQTM AFVYESYRWR PVTAGGFPHK ATKDIIWQNY LIPKGATVVG NVWAVGRDPD
YFPDPERFDP QRWLDSNGKL REDVKSYPFG FGRRVCPGLH MATASVFLNT ALINWAFSIH
TDPESPIDDM AFTKSANAHP MPFKVIFKPR VTKTMEGVKE MMEDYGI
//
