ID A0A409W9J1_9AGAR Unreviewed; 634 AA.
AC A0A409W9J1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 13-SEP-2023, entry version 15.
DE RecName: Full=Actinin-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CVT24_010127 {ECO:0000313|EMBL:PPQ75187.1};
OS Panaeolus cyanescens.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Galeropsidaceae; Panaeolus.
OX NCBI_TaxID=181874 {ECO:0000313|EMBL:PPQ75187.1, ECO:0000313|Proteomes:UP000284842};
RN [1] {ECO:0000313|EMBL:PPQ75187.1, ECO:0000313|Proteomes:UP000284842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2629 {ECO:0000313|EMBL:PPQ75187.1,
RC ECO:0000313|Proteomes:UP000284842};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ75187.1}.
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DR EMBL; NHTK01005694; PPQ75187.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409W9J1; -.
DR STRING; 181874.A0A409W9J1; -.
DR InParanoid; A0A409W9J1; -.
DR OrthoDB; 2872403at2759; -.
DR Proteomes; UP000284842; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000284842};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 16..122
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 124..230
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 485..520
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 634 AA; 71711 MW; 9E0FD025D0494641 CRC64;
MGFANMVETA ESRSRDMQER TFCKWLNTKL EANGYPPMSS LVRDLSDGVR LIQLMEIMGD
TSLGRYNKNP RIRVQKAENV NKALEFITSR GVKLTNIGPE DIIDGNLKLI LGMIWTLILS
EEGLSAKEGL LLWCQRKTKG YEDVDVQDFS YSWQDGLALC ALIHCHRPDL LDYDKLDKTA
RHDNTRLAFT VAAESLNIPP ILEVEDLCDS AHPDERSVMT YIASFFHAFS TMDQEETIAR
RVEKFAELMQ SVWVIRNDYE RRMQQLLAAI QSTISAWSST VFTSSYADTK TLQSAFLAYK
STTKREWVAE RQDVATLFSN VQTKLKTYGM REYVPPEGLK LEDLEERWAE LTRGERERGR
RINEMIRAIK EELRKKFANL ANAFSARLDN LNRELAQLSG PLEDQQAYIK NLTTTLIPSL
TELLQEVVDA EEEGDKANVE ENDHTVFTAS DLQFELSLVV KSINAKAAFI ENQIVSSKQT
NLSPSQLETF ESTFRYFDKD GSNTLSHPEM IAALASLGIV YGEEDMDAIF NDLVDMFGAV
TFEAFVALLV RIVQDHGGAE QVHEAFEGVA RGKAFVTELD LRRAHLPVQT IEYLKSAMPR
AEGVEGEDGA YDYSAFIDAV FDDPEDYLPN GDVS
//
