ID A0A409WAB2_9AGAR Unreviewed; 601 AA.
AC A0A409WAB2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=FAD-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CVT26_016218 {ECO:0000313|EMBL:PPQ75444.1};
OS Gymnopilus dilepis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Gymnopilus.
OX NCBI_TaxID=231916 {ECO:0000313|EMBL:PPQ75444.1, ECO:0000313|Proteomes:UP000284706};
RN [1] {ECO:0000313|EMBL:PPQ75444.1, ECO:0000313|Proteomes:UP000284706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRW20 {ECO:0000313|EMBL:PPQ75444.1,
RC ECO:0000313|Proteomes:UP000284706};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SIMILARITY: Belongs to the PheA/TfdB FAD monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007801}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ75444.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NHYE01005259; PPQ75444.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409WAB2; -.
DR STRING; 231916.A0A409WAB2; -.
DR InParanoid; A0A409WAB2; -.
DR OrthoDB; 1386239at2759; -.
DR Proteomes; UP000284706; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:UniProt.
DR CDD; cd02979; PHOX_C; 1.
DR Gene3D; 3.40.30.20; -; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012941; Phe_hydrox_C_dim_dom.
DR InterPro; IPR038220; PHOX_C_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43004:SF20; 2-MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13660)-RELATED; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF07976; Phe_hydrox_dim; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000284706}.
FT DOMAIN 11..380
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 416..566
FT /note="Phenol hydroxylase C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07976"
SQ SEQUENCE 601 AA; 66795 MW; 74CA0A62CDA0DD77 CRC64;
MMTTLAAKVT DVDVLIIGAG PAGLMACNAL AKNGIDVRII DQRPEMVAAG QADGIQPRTI
EVFQSYGLGE RLLKVGNQMH MAAFYNPSPS GGIELTDRVP DVTASTARYP FEVTLHQGAI
ERIFLDSMNK FGVKIDRPVV PTSIQLSVDE SSLNDPNAHP VQVVLNHIMA DGKSETEIVR
AKFVIGADGA HSWVRKAFNI EMEGEQTDYI WGVVDLTPDT DFPDVRNKSA VHSNSGSCMI
IPREGDKIRL YIQLDGKSSY VTNNGRIDKA RLQPHNIFEH ARKAFHPYYF KNPEKFDWWT
IYIIGQRVAS TFSVKDRVFI VGDACHTHSP KAGQGMNASM NDSHNLSWKL THVIRGWAKM
SLLKTYEFER RKYAQDLIDF DKKFAKLFSG KPRTEEYQDG VSHEEFLQAF QTFGGFTSGI
GICYADSSIT NLKFQSIAKN LLIGQRLVPQ VFLRAADGRP VEIQDLIPSD SRFKVLVFTG
NSSDAGQLQK VKDVSQELED ALSRLSAGRT SSFFDTIPIS SAKKTVVRYN DLPKFLWSHW
SKVLIDDKDV KGSQGGDGYD NYGIGANGAM VVVRPDGYVG MVAPLDGVVE LDRYFRGFLQ
L
//
