ID   A0A409WGX5_PSICY        Unreviewed;      1095 AA.
AC   A0A409WGX5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN   ORFNames=CVT25_011197 {ECO:0000313|EMBL:PPQ77762.1};
OS   Psilocybe cyanescens.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX   NCBI_TaxID=93625 {ECO:0000313|EMBL:PPQ77762.1, ECO:0000313|Proteomes:UP000283269};
RN   [1] {ECO:0000313|EMBL:PPQ77762.1, ECO:0000313|Proteomes:UP000283269}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2631 {ECO:0000313|EMBL:PPQ77762.1,
RC   ECO:0000313|Proteomes:UP000283269};
RX   PubMed=30283667; DOI=10.1002/evl3.42;
RA   Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA   Matheny P.B., Slot J.C.;
RT   "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT   diversity.";
RL   Evol. Lett. 2:88-101(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPQ77762.1}.
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DR   EMBL; NHYD01003434; PPQ77762.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A409WGX5; -.
DR   STRING; 93625.A0A409WGX5; -.
DR   InParanoid; A0A409WGX5; -.
DR   OrthoDB; 1449900at2759; -.
DR   Proteomes; UP000283269; Unassembled WGS sequence.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd06869; PX_UP2_fungi; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR024554; DUF3818_PX-associated.
DR   InterPro; IPR024555; PX-associated.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR047168; YPR097W-like.
DR   PANTHER; PTHR47185; PX DOMAIN-CONTAINING PROTEIN YPR097W; 1.
DR   PANTHER; PTHR47185:SF1; PX DOMAIN-CONTAINING PROTEIN YPR097W; 1.
DR   Pfam; PF12825; DUF3818; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF12828; PXB; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000283269}.
FT   DOMAIN          197..355
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          251..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          851..1068
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..318
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        851..883
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        982..999
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1010..1032
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1095 AA;  123141 MW;  64E89A181037BB27 CRC64;
     MPNTNRPDNP APLEDDDSTA TTTNKSDLTP LRAHYLKKAL VQLQFARELD LISTEGPPNV
     STLSYLGPPF TPPPKDTSPL DLPFLRYIFR QFVLTFPFMA AAPKDFYSLK LQPFVGAVLA
     RNISPTSVLD DADSEQATRK KLLAKVERNL SLFVNAATKL VEPEEVVRLT QADLDRLEIL
     SRKRQKRLAK ERDLFEVNIV SVRTVIDKGR MRSRAHEEFI IRTRRSRYPD VYVSRRYGDF
     RTLAAELAKK HPQEEIRLPP AKDKTYSAAP SITPTTSHPP MSPLSRQSTS STFNDYNLNS
     PTGSHSENLP SNPSRLTREK NRLTLRSYLN TLMNSSTIAS SPVLRSFLLS GPTTMTSEEL
     EDAKRREEAD RVREEGRKKF AKEIAGRVEG LREAVKSVKG DIMGKDGLTH IFATIKVTPD
     IRDLPSNYHA VVEWARISLT SLASTVFQMF IASDDASETF SGLKRIHGLM PYFMMKTALK
     ITNPVFWISF LLNHSEAEAY YNGKKESNPY PTLSNIFFSR MFTSSLTEEV KALEEEIEAV
     KEKVDDPIMC EKVRQFVYAP REIQTMFKND AAAEQMHVLT IVLRSAENPV LSRAQMHRLA
     RAHKAHIIYT KHRETLEDSD DDDGPQDEDA WLLEDLKVLA ALYSKLKDRE QLIELIFEGF
     TSELLKDIIT IFYSPLAQVY RAASIADSLS DLQNFINDLI KTVEQVEGLS QDDPHLTVQA
     FINLIIRHEQ SFYHFVHKVH SKGEGLFDNL MHWVELFLTA VREGLGEPIS LEYLLPHKGQ
     ERADILFEVD KIAQYHYKLK VLYEDKLRRR FGRAQSNEAD AEDEATQALV NGVVGEISFG
     DLVQGDAVDL AAEETDEETS SDEDYSSSEY ETGSEDASDD DSEESRTDPA KPRLPPPLPS
     SPLSPSHSRI SHPNDRQPRN HTRNNLPRHA MHKSAAGSSS TLAYPSAPSA PPEPKRKRSL
     SLHRAKSLTF SLGKRNQDVP PVPSMPTTPS VPPVPPVPSV STTLRMTRPA PSRPLPPSPD
     SDGPPPPVPL KDLPLEKNQV PDSTPLNVPP KSVTVAPKKK KLTQGLKPPE LQHIPQLLPV
     FAEMMKPLLR LRQPQ
//