ID   A0A409WJY8_PSICY        Unreviewed;       745 AA.
AC   A0A409WJY8;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein {ECO:0000259|Pfam:PF09995};
GN   ORFNames=CVT25_002431 {ECO:0000313|EMBL:PPQ78863.1};
OS   Psilocybe cyanescens.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX   NCBI_TaxID=93625 {ECO:0000313|EMBL:PPQ78863.1, ECO:0000313|Proteomes:UP000283269};
RN   [1] {ECO:0000313|EMBL:PPQ78863.1, ECO:0000313|Proteomes:UP000283269}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2631 {ECO:0000313|EMBL:PPQ78863.1,
RC   ECO:0000313|Proteomes:UP000283269};
RX   PubMed=30283667; DOI=10.1002/evl3.42;
RA   Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA   Matheny P.B., Slot J.C.;
RT   "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT   diversity.";
RL   Evol. Lett. 2:88-101(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPQ78863.1}.
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DR   EMBL; NHYD01003403; PPQ78863.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A409WJY8; -.
DR   STRING; 93625.A0A409WJY8; -.
DR   InParanoid; A0A409WJY8; -.
DR   OrthoDB; 2728050at2759; -.
DR   Proteomes; UP000283269; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR   GO; GO:0019408; P:dolichol biosynthetic process; IEA:UniProt.
DR   CDD; cd00475; Cis_IPPS; 1.
DR   Gene3D; 3.40.1180.10; Decaprenyl diphosphate synthase-like; 1.
DR   HAMAP; MF_01139; ISPT; 1.
DR   InterPro; IPR018713; MPAB/Lcp_cat_dom.
DR   InterPro; IPR001441; UPP_synth-like.
DR   InterPro; IPR018520; UPP_synth-like_CS.
DR   InterPro; IPR036424; UPP_synth-like_sf.
DR   NCBIfam; TIGR00055; uppS; 1.
DR   PANTHER; PTHR10291; DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10291:SF44; ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF09995; MPAB_Lcp_cat; 1.
DR   Pfam; PF01255; Prenyltransf; 1.
DR   SUPFAM; SSF64005; Undecaprenyl diphosphate synthase; 1.
DR   PROSITE; PS01066; UPP_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283269};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        342..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          117..344
FT                   /note="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase
FT                   catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF09995"
SQ   SEQUENCE   745 AA;  84413 MW;  1D69F24869781605 CRC64;
     MASTVARPTI SPKTSLLFLA EEGKDFISSS EKVSGSTESD GSTFFGLMPK ALDIRSSFRL
     VLLLVILSPL YRGYFTYRTC FAVVVASYAG PAIIRTRYPR FMEVNILDDL RIEAGATLSL
     FASITALLLQ AHNTSISIAV KFHSEFYSRP LTRLLRTYLY VEMALNGTSE EKEQTASWLR
     WMHRHIHGSI TDEMREELGI PEDVETYGYI DELKAYIMYT LTWATISFQT RFGRPLSKRA
     KDTIVLEYAC AGMRIGVPQD LLSKDYDSFL IAFDQRLDIL DAGYSLTRVI VENVEGSVLS
     AKKNIITAIL VRIALMIGYD LLPTRVREKY QLKILSTWWQ RAIQKILIAV LWVIYPMLMW
     VPLRGMICLL LVLEPQLRSI FMSSLQAIHS MDILSDKPVY SKGDTSAPKS EEAIAYELPS
     YLLWLESGKD GRPFLQAVLV RILATQLNSA QAASQSRWSA GRLMPWLQLP GRLFALALES
     IRQNVVDMVS CWRTQLKESM TFNGEEVKMP LHIGFVMDGN RRYARNLGQP IIVGHQRGAQ
     TAGNILEWWL RFMPNAAKYS HKSLGPQYLT VWAFSAENFK RTQEELDGLF RLMTAEFKSL
     AYTSIVHLFQ IRVRVIGSRD GLPRELLDSI ELLEETTGMY SRLYLQVAVG YGGRDEIVRS
     VNSALARGEE ITEDAISRGT FCASVGVPPV DLIVRTSERR TSGFFLWDTQ TAELHFINKL
     WPELNEGDWL DAVASFAVRE MRGGK
//