ID   A0A409WNQ5_PSICY        Unreviewed;       778 AA.
AC   A0A409WNQ5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=DUF300-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CVT25_001435 {ECO:0000313|EMBL:PPQ80136.1};
OS   Psilocybe cyanescens.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX   NCBI_TaxID=93625 {ECO:0000313|EMBL:PPQ80136.1, ECO:0000313|Proteomes:UP000283269};
RN   [1] {ECO:0000313|EMBL:PPQ80136.1, ECO:0000313|Proteomes:UP000283269}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2631 {ECO:0000313|EMBL:PPQ80136.1,
RC   ECO:0000313|Proteomes:UP000283269};
RX   PubMed=30283667; DOI=10.1002/evl3.42;
RA   Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA   Matheny P.B., Slot J.C.;
RT   "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT   diversity.";
RL   Evol. Lett. 2:88-101(2018).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM184 family.
CC       {ECO:0000256|ARBA:ARBA00038513}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPQ80136.1}.
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DR   EMBL; NHYD01003345; PPQ80136.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A409WNQ5; -.
DR   STRING; 93625.A0A409WNQ5; -.
DR   InParanoid; A0A409WNQ5; -.
DR   OrthoDB; 166432at2759; -.
DR   Proteomes; UP000283269; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005178; Ostalpha/TMEM184C.
DR   PANTHER; PTHR23423; ORGANIC SOLUTE TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR23423:SF10; TRANSMEMBRANE PROTEIN 184C; 1.
DR   Pfam; PF03619; Solute_trans_a; 1.
DR   SMART; SM01417; Solute_trans_a; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283269};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          520..670
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          682..736
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..560
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        565..616
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        644..666
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        700..736
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   778 AA;  86728 MW;  F38A7F2677A8CDD5 CRC64;
     MAGEGAGSRL PTWLLLVAGL SALIAVLVSM MSIFLQLRNY RKPSLQRMVV RIMLMVPLYA
     IASLISLFSV EAAFVIDAIR DVYEAFVIYC FFVLLLSYLG GERSLLILLH GRPPKEPVFP
     INLVKREIDV SDPYTFLFLK RGILQYVQVK PILAAVTLIL KAVGKYNDGD FRANSGYLYV
     SIVYNPCSGY ASTTTSNLSG KETIFITPKV DANIGYSPVP KFLCVKGILF FSFWQSIAVS
     TLVAARVIRK LGPYTDPEPV SVGINDLLIS VEMPFFAFAH MYAFSYKDFM DPTHTFVARM
     PMYYAFRDAF GLLDVIEDTK TTLRGEGMDY REFEPAEGFM HQGAGRDRRI RAGLRYSKGG
     QRKYWLPKAT EDTQPPGRVE RITNKVIKRI AGADQAETVT APLLPQDAEN VVHLAPDLQD
     TTDDTVWGDP SVEDGYDLPF GDLDDGDEEL FAHSKRYLFG DYNYPCIDVS SESARTLMWT
     EEERVLRDER GAWFSPIRGA QGQAAMQNRT RPVWEGYGAV DNSQLHPQSK KLQAKSPERF
     FSDDTQEQRL IDHDARAAEP TDVSLRWTKT KSHSRPGASS RSPAQNIRTV QQQSARHTPS
     SSVASASGSS RGDVRSPPSL SREPSRPKAG DSPVLPPDAV DLVVEDKAAA EEDLTRERRK
     GEPATRGGSG LRRIYRRGFV AQGEDGERAE GEVEVEEQAE DAEDARRVEV GEEIVHAIGD
     DSGDDEEVER FPRTSGHSDW VQDVQVEGVV ARTGTPPLHA RVEAYQYHDI PEDDNPWA
//