ID A0A409X252_PSICY Unreviewed; 349 AA.
AC A0A409X252;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=Heterotrimeric G protein alpha subunit 4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CVT25_015123 {ECO:0000313|EMBL:PPQ84829.1};
OS Psilocybe cyanescens.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX NCBI_TaxID=93625 {ECO:0000313|EMBL:PPQ84829.1, ECO:0000313|Proteomes:UP000283269};
RN [1] {ECO:0000313|EMBL:PPQ84829.1, ECO:0000313|Proteomes:UP000283269}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2631 {ECO:0000313|EMBL:PPQ84829.1,
RC ECO:0000313|Proteomes:UP000283269};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ84829.1}.
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DR EMBL; NHYD01002801; PPQ84829.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409X252; -.
DR STRING; 93625.A0A409X252; -.
DR InParanoid; A0A409X252; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000283269; Unassembled WGS sequence.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0007266; P:Rho protein signal transduction; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000469; Gprotein_alpha_12/13.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF242; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00440; GPROTEINA12.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000283269};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT COILED 14..41
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 349 AA; 40176 MW; 277149C5FF7FC89E CRC64;
MGACMSAPAG VEISEQDRIL HREAEKQLKE AKAKLASQVK VLLLGSGDSG KSTILKQMRL
IHKVPFSAQE IEHYRQLVFD NLTRGLRYLL DAMEDMELAV SEENLPHLEL IDGVRDIRDG
EPFPVAYYMP LKSLWEDPDV QKAWARGNEA ALPENLSYFY EDLERLFDPA YQPTEQDIIR
CRARTIGITE TTFTLREHEM LMVDVGGQKS ERRKWIHCFQ DVTSILFLVS LSGYDQCLVE
DKDANQMQDA MTIWDSICHS QWFKQTSIIL FLNKNDLFEK KIPSSDIKNF FPDFEGEPGD
VRAGREYFKR RFARLAQKAG RSKEREIYIH ITTATDTALL RVVMAAVEE
//
