ID A0A409X6V9_9AGAR Unreviewed; 580 AA.
AC A0A409X6V9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=CVT26_008820 {ECO:0000313|EMBL:PPQ86519.1};
OS Gymnopilus dilepis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Gymnopilus.
OX NCBI_TaxID=231916 {ECO:0000313|EMBL:PPQ86519.1, ECO:0000313|Proteomes:UP000284706};
RN [1] {ECO:0000313|EMBL:PPQ86519.1, ECO:0000313|Proteomes:UP000284706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRW20 {ECO:0000313|EMBL:PPQ86519.1,
RC ECO:0000313|Proteomes:UP000284706};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ86519.1}.
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DR EMBL; NHYE01004050; PPQ86519.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409X6V9; -.
DR STRING; 231916.A0A409X6V9; -.
DR InParanoid; A0A409X6V9; -.
DR OrthoDB; 1654409at2759; -.
DR Proteomes; UP000284706; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47642; ATP-DEPENDENT DNA HELICASE; 1.
DR Pfam; PF05970; PIF1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000284706}.
FT REGION 511..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 64635 MW; 896104C750D55BB7 CRC64;
MIQEFTLNTE QARAFRLVAE HSLDRRNEPL KMYLGGPGGT GKSRVINALK EFFSRKGQSR
RFRLASFAGI AAKNISGMTV HSALLLNQRG GKAAQSKTKR DLVSSWEGVD YFFIDEVSTI
SCKLLSDISD ALVDAKSNTA PFGGVNMILA GDFAQLPPVR ATRLSAAVDT NPARTTKPYA
QGIVAGKLLW QSFTKVVMLT QIMRQAGNEN KDFVDLLMRL RTGTCTDDDH ATLSHRLIQN
QDVNPRDWED TPIIVSGNAQ KDALNDYAAA AFAARTNQEL HWYHAVDTHR GKQITDGTLK
RHLQSLHSGL TNQRLGKIPL VIGMPVMIGQ NYDLEGGIVN GCMGKLRKIR YKEDEHGNRY
ATSCVVECDS ISCEALHGLP PNHAVVLEDT VDMTFEHPHS GKKCKIKRTQ LPLTPAFALT
AHKAQGQTMP KALVDIQSCR GTESPYVMIS RVTSLQGLLI LRPFDTKKIK CRQSEDVRKE
MTRLETLRWQ TIAEIGSLAE KRTARKMLKT RIDREQESYS VNQPLKRPRK VSQNDNQSNV
KKRRIAADVA PSYGDQGLEM DVDIDHADAP LRIPKKVQVL
//
