ID   A0A409XDF2_PSICY        Unreviewed;       929 AA.
AC   A0A409XDF2;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|Pfam:PF05729};
GN   ORFNames=CVT25_008625 {ECO:0000313|EMBL:PPQ88754.1};
OS   Psilocybe cyanescens.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX   NCBI_TaxID=93625 {ECO:0000313|EMBL:PPQ88754.1, ECO:0000313|Proteomes:UP000283269};
RN   [1] {ECO:0000313|EMBL:PPQ88754.1, ECO:0000313|Proteomes:UP000283269}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2631 {ECO:0000313|EMBL:PPQ88754.1,
RC   ECO:0000313|Proteomes:UP000283269};
RX   PubMed=30283667; DOI=10.1002/evl3.42;
RA   Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA   Matheny P.B., Slot J.C.;
RT   "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT   diversity.";
RL   Evol. Lett. 2:88-101(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPQ88754.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NHYD01002032; PPQ88754.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A409XDF2; -.
DR   STRING; 93625.A0A409XDF2; -.
DR   InParanoid; A0A409XDF2; -.
DR   OrthoDB; 1608130at2759; -.
DR   Proteomes; UP000283269; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR   PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000283269};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          252..443
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|Pfam:PF05729"
FT   REPEAT          827..859
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..100
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   929 AA;  103658 MW;  4380AC574D9E6F75 CRC64;
     MFDIFKRCIS PAHSEQSQGS SSKSRSLWPK SFFKSPSMRP TQPTSSPPLA PSTAHSRGET
     ALDEPKSSAQ QATTTTTSLD QSRGLASNPP EDSQTMPKTA STQLETVEKE LGDWTPKTQE
     GQWIDQFKLT LEDELDKLIQ LSKEWLVRKV ADHEDEKTHI TGTFEHINEA RVQFEPAIGI
     RVFKSVYNME SALRELLFNR LTPSKIADHK YHLEGQEEQC VQRKVCTPGT RVCILGGIVT
     WAKNTSSGSP NVYWLFGQAG SGKTTIAYNV ARHFEFAGNP NNTIILGGNF FCSRQFEESR
     LSKCIIHTVV HHLALKCREF ADQLSDFNTV NQSVHAQLKD LLMGPWQASK PARCHDPSKP
     PLHYLIIIDA LDEIDGTGGS KFLQELLNAL DKNENCLQGL KFFVTSRPDP NLVRHVDSLK
     SKQLYRLEEV PPEEAQDDIR TYLMAELPHF AGGEEIKGLV ELTARLFIYA ATVMKYLVTC
     GQSEQQTFLT TLLASSNSFN LQSLSNRMPF TLLDTLYSQI LNEAFCDFIP EEKEWKDRCS
     ILHTFLCTTE QTSTSVVADL LFTSDYTDVA EKLLSDLHAV LYREDGRVLA YHKSFSDFIF
     TEARSGNFWC DQAKHHRLLA ESCFQSMRDG LRFNIANISS SFVLDVDDPG LADAVKLNIP
     LVLSYSSRNW SYHLSAAAPT IPDGLHDSIS DFLQLCALFW IEAMNLLGLH GLCGSMLRTA
     HDWVMSSQGS FSLAECLTEA RSFALYFSGS GASSSTPHLY ISALATWPRN LEPCRGWKTH
     FPRIPSFTSA SLGGTLLMTL NVNSQVIAVA VSPNGKHIVS GSYDNLVQGH KNWVTSVAFL
     PDGKQIVSGS NDSSVQVWDF GSLYIREMIS EKHTGWLLSP DGQHRLVFVS PEFLLPDASN
     ILTIPRSSCS SVDFVHAALG PHWKECYCL
//