ID A0A409XFZ6_PSICY Unreviewed; 2215 AA.
AC A0A409XFZ6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Cytoplasmic protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CVT25_012229 {ECO:0000313|EMBL:PPQ89557.1};
OS Psilocybe cyanescens.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Strophariaceae; Psilocybe.
OX NCBI_TaxID=93625 {ECO:0000313|EMBL:PPQ89557.1, ECO:0000313|Proteomes:UP000283269};
RN [1] {ECO:0000313|EMBL:PPQ89557.1, ECO:0000313|Proteomes:UP000283269}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2631 {ECO:0000313|EMBL:PPQ89557.1,
RC ECO:0000313|Proteomes:UP000283269};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ89557.1}.
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DR EMBL; NHYD01001859; PPQ89557.1; -; Genomic_DNA.
DR STRING; 93625.A0A409XFZ6; -.
DR InParanoid; A0A409XFZ6; -.
DR OrthoDB; 8258at2759; -.
DR Proteomes; UP000283269; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08679; C2_DOCK180_related; 1.
DR CDD; cd11684; DHR2_DOCK; 1.
DR Gene3D; 1.20.58.740; -; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR043162; DOCK_C_lobe_C.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR046773; DOCKER_Lobe_C.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF10; MYOBLAST CITY, ISOFORM B; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF20421; DHR-2_Lobe_C; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000283269}.
FT DOMAIN 691..893
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1627..2038
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 20..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2093..2120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2132..2163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2140..2163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2215 AA; 247627 MW; EC7A07B7C8F4E480 CRC64;
MWEPLPLIVY GYAVHPLTPS RRETRHSSRN RLSTVTEAST DDHSVMRDVV TLEVGDEIYA
FEKYVPSPRD QVEGIWYRGY VLCTTRRPPV TWSLSDPSSS TSQNRPSVKA EETQQVFIGI
FPASHIFVRD ELADAEGRLP DLARTLQGGY SAGNSAGIQG RGSPGDALGN WNRDKASIGM
VTVREDEDDS DAYMSRKSFK LGPPPDQANS SRAALPVYPT SLRSSSPADS HVMKPLPPRP
SRKSGDDTAS GAQQPIIDEI ASALREWHTL MFQYLARRDY KLFHIVREHI EALHLGRRQL
LAQTLSAEET VNMRRDCVTR LVSGNLVQGL DVIVRHPTWG GLVTVDVEGE TDPRSWVSAV
RMYAMQVSLA YLNVTYDDSR PYPLGPSTEY VPSIPLPTPA HSAFPDFLHH KNRSRSQGWL
DPDDPLKHSA AKFYHVFLDI RAFVASPCTP GETAELFFSL YRKQGTQFVT EEFCAVLNHN
GVLARDPTSR IRTLFVDLAA SDIQDPIYLV CRIVRNGALK IGSSVSSSTL GDGRRGSETS
LRTDSLSPTT ITWNDSITAS TSTLVSPSSA RLNGFGESVQ FRRPFGCAVL ELTQLGKMVS
EQADVSPLRE YTMPIYIPTN EASFSMIHQN IINNNTKEFE KSPRAEGLAV SVKVFRGNAK
TVVRENTSLL QDTPHTLRLG FPDVVFPGDA RNELYIKLWC GDFTASHTGS GRLSVANFAR
GQIGQPSVNV QITVEVKDQH GNTIENVISQ GSGEPLMTQF NSMVFMRCNE PTFGELIKIQ
LPLNDVPQWH LFFTFRNRSS RSSSKNLAEG SDRPFAFAFQ PLFPDASAFV EDGSHTLIMY
RADKLGQLVP SAYLSAPSRL SAGQKLEHIP MPTDFLRLSS PLKDTLTIRS SLCSTKHTQN
SVLLRLLNWE KQDKEYLAPL LTKFTFIGEG EIVKFLRDIF DSLFGILVSQ NNQSGELDHL
VFNALVTILG IVQDRRFSNF QPVLDVYIEK HFNCAAASSH IIHSMDQLVM NPTSAETASP
LRAALKVWHY IFKFIARSRE LQKVKEVGMG GGATVDYLET SFKRELRSHL SNFTQMMATS
SPPSIIGTQT IALQHFTSIL PELAKIYTTV ELVSIATTFA NAVTVGKGKI VIWKLIMYLQ
IVKSFLFDNA ESRPFLVEAV VIWIKPHFGR YDEYAHTSSN DSEAARDAAR VTWLESIRLC
VTIIAVMLDK LQQNLTNPTI VSDRVALIKE QDNVELLLSL IPRLLDSYRE IQSPASKKAI
EKTKAPSTIK SSIPVTFPES YPFSLVSSLP EPPSGVSNLP LTQEGESLFY PGLGEVAIVF
LVLILSSPIK HIITFLESSL DIEGRERFVG LLSQFFKVAT SLLENDAFPK AWMNVNILAH
KVLIKIMDPI ASIMEKEFIP PQEFESRFDA SLWREGLHML LKLLSSEQLM IEDFSPQKRR
AVWRLTGDIR GEGAAILLNL WQALGSAEHV STSGEPAMRY GATVIDLFLC GYQIYLHALV
GHVVNLCLSH HDQLRNNAVQ ILYSMIVSEY HQSEHFDGIE NELVTRLDSL FMSDSKGDDI
SRAFFIGQLR HMFDTSDVDE QLRDQLSNFL DSVDLFLELL LSVRALPEGE EYADDRVIAT
LRLMNFIRRI GRDEIYIKYV HQLVNMHLQS QNYVEAALTL KLHSDLHAWD LNSFVPPMED
LGLPQQSHFH RKETLCLLIL DYLGKGKAWE SAIEICKELA YQHAEVTFNY GRLSEILRHQ
ATLLEHIVTD QRYYPDYYRV TFYGSFPAAI RDKRFIYRGY EWEKFGAFCE RMLNKHPEAQ
LLKTAGDPPV DIRYGNDQFI QCTAVTPEPD RDLPVFTNPD VPLAVRTYYE HSGINLFSSS
RQIRKTTRDG MEEVWTEKTY YTTEQVFPTV LRRSEVVNVE FVEISPLENA LQEVEEKTKE
LAGLHLKYQA LAKTTQNVST NALAMCLNSA VDAPINTGVA SYRQIFFSPD YIARNPERAE
LVEKLRQAID EQVRIIDSCL KLHGLLCPPE FIPFHETLEK FFKKNFRDEI RRLAVDSDSI
AVSTRSQNMG VGSSSGVQYP IASSSYEQSV KRSLSTSSTA RFQIPPLNVG RSILTPTLES
PMSPGESSPH PNSASKQTPL QRHLAHLARH GINGVSSAPG DLAGTDSLSA ESPHNSFVNV
GNANGNGIHG TSAGQVSGAS VATSYMGSMG SFGSLKGRFS RFGSLNFGRR GGSNS
//
