ID A0A409Y195_9AGAR Unreviewed; 553 AA.
AC A0A409Y195;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=G-alpha-domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=CVT26_006215 {ECO:0000313|EMBL:PPQ96814.1};
OS Gymnopilus dilepis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Gymnopilus.
OX NCBI_TaxID=231916 {ECO:0000313|EMBL:PPQ96814.1, ECO:0000313|Proteomes:UP000284706};
RN [1] {ECO:0000313|EMBL:PPQ96814.1, ECO:0000313|Proteomes:UP000284706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRW20 {ECO:0000313|EMBL:PPQ96814.1,
RC ECO:0000313|Proteomes:UP000284706};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ96814.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NHYE01001321; PPQ96814.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409Y195; -.
DR STRING; 231916.A0A409Y195; -.
DR InParanoid; A0A409Y195; -.
DR OrthoDB; 1864818at2759; -.
DR Proteomes; UP000284706; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000284706};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 43..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 76..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PPQ96814.1"
SQ SEQUENCE 553 AA; 62247 MW; 5081E1A56658FC6F CRC64;
GDASALSESV GPFEDTRKLS IPLPATNPPL LLVMPKLSAL RRRSLRDDPE RDDPLARAIA
PPENETPGEY SARLAAEEEA QKRSDAIDEE INRQRLENKR APKSIRVLLL GQSESGKSTT
LKNFQLINST KAFRHERASW RAVIQLNIVR SIRLILDIVS EAHATTAGNI TPIRTSQRHL
TDSIDLFPPQ TRPAVTSELL KLRMRLLPLQ QVEEVLLRKM TPAGSAEFEA THLSPMTNVP
YRARQGKFKE IAINSTAQWK GAFGRLIATA RASLDSAADI DFEDPKDPGV ILNACAEDIA
KLWNDPIVRA LLKAQNIRLE SMSGFFLDSI TRVTALRYVP TDDDILRARL KTLGVSEHRF
TLKSAGEHFI VYHWPYPRMF SQEVWSAKTG GYMTLGAHAL CEVAAWAPYF DDMDAIIFLA
PLSGFDEVLA EDPSINKLED SILLWKHVVS NPLLKDTQII LFLNKIDLFK AKLEAGIQFS
EFVVSYGTRP NEYEPTSNYI RKKFGMLLKQ HSPVPRIYYS HLTSMTDSKS THQILMNVKD
MVIREMLHKS SLV
//
