ID A0A409Y3U7_9AGAR Unreviewed; 2209 AA.
AC A0A409Y3U7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=CHAT domain-containing protein {ECO:0000259|Pfam:PF12770};
GN ORFNames=CVT26_001870 {ECO:0000313|EMBL:PPQ97687.1};
OS Gymnopilus dilepis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hymenogastraceae; Gymnopilus.
OX NCBI_TaxID=231916 {ECO:0000313|EMBL:PPQ97687.1, ECO:0000313|Proteomes:UP000284706};
RN [1] {ECO:0000313|EMBL:PPQ97687.1, ECO:0000313|Proteomes:UP000284706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRW20 {ECO:0000313|EMBL:PPQ97687.1,
RC ECO:0000313|Proteomes:UP000284706};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ97687.1}.
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DR EMBL; NHYE01001208; PPQ97687.1; -; Genomic_DNA.
DR STRING; 231916.A0A409Y3U7; -.
DR InParanoid; A0A409Y3U7; -.
DR OrthoDB; 1614914at2759; -.
DR Proteomes; UP000284706; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 6.
DR InterPro; IPR024983; CHAT_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF12770; CHAT; 1.
DR Pfam; PF13374; TPR_10; 2.
DR SUPFAM; SSF81901; HCP-like; 2.
DR SUPFAM; SSF48452; TPR-like; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000284706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 114..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1931..2208
FT /note="CHAT"
FT /evidence="ECO:0000259|Pfam:PF12770"
FT REGION 1907..1927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1909..1924
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2209 AA; 243342 MW; ED1AAA378AF89570 CRC64;
MDSSIDELIS AVRETKVASY MWGQFMGNRS GLAFLVCDAL STLSREVEYI WRLVEYNQVS
QGGFITAVEQ RKMVECKRAI SFHEILDAIP NGSNRISFST RPSKNLSRGL NDSVPLVSSY
YVKFPLFGGI LWVFTMGIFR GGYAILLLAV DVIFSIRLYA LYKRSKKILA LLISLVLGEF
VVQAYVASKI GASTADTLFL TPSTLPILGC LTSPDLRITT PSWQVPGERP NMFDDSDMSP
LAIYFVLMLF KFYESVQLTK VVGLRSSLPP LIRAFVRDGT IYFLLVLVTL LAGALDSFLT
KGPYVALYAP CTVASLAITV SFEALVSSSI YEKPQLLIMQ PTLTAKREIW KPFALPTGES
HCTRFDLEFW GRPQQSAPTF KSSRGTSTIT AMTTRAESTH FAHETVEGGL ADVDRVLTLV
ERCLSDVPSA DLEKTISLLQ ELIADVGVSS NVRMNSLLGL AVSLGVKFAR SKGQEGLQEY
LEVESKMREV STASTPDQDF LEEGGTRLRN LKAAAQKSLS EIRESMALSL FSIDVSMPFL
HQCLVILPAS HPKRIRVVQT LGNVSFLQFA SQLKNTAEMK FATLVIRHNL QTFDENEQWG
LQRYLQFLEA SVSIAQMYGL RMKDRAEPHS TPSAGMSSLD EESTQILEHQ ADPQTEVADI
STAIGSLPTE LTATDYTMNM GSQAKALFLQ FTQDGDVGVL QKSILLSKQA LQLIPAAHPE
HFVVLTNLGS GMQALYHQGG VHENLDEAIT LFKRAAGSVP ANHPLWIGSL DKLAGGLYAH
YHCTSNPEDL RDAILLSKRA LELRSPEDPD LCVTLNNLAT GLLAQFEQEG NSQILQEAIS
LSMQALKLTL QLPIHRVASL SNLSVGFHLR FEAEGKLQDL ENAISFSRQT LQFRTAPHPE
RYMNLNELAN QLLTRFEHQG RVSDLNEAIS LHSEALELTP PPHPAHTISA NNLANSLLIR
AEAEGSGNSR DIDKAISIYK QILQLTTLPQ NRIDPLNNLA GGLVARFDQQ GNIQDLEEAI
LLYKQALELT PISHSTRPQS LAVLARMHLN MFELRGNPQH LDETISLSKQ ALELTPPPHR
HRVPNLKNLS LGLQKRFEQR GDAHDLDEAI AVDKQVLELE TEPDSDRVQS LDVLSQALLT
RFYQQGHSQD LDEAITLCEE ALHLSPKPDS DRADSLNNLA SALFARFEQH GNVQDLNNSI
ALCKRAVELE HRSGQVQATT DHADHATALP KRSQQLGSDS VIDDNISFLR QTLERMPIGH
PSRAFLFNSL GLALQSRFDQ QGEAQDLDDA ITVHAQAIES TPKFEAIYVE LLINLATELH
MRYDHKKDLD DLFNAVLRFR GAIDMLSPSH PARPTTLINL AITLLAQFRS KGDEQDLNDA
IAVSKEALTF EYPSHSVRAA LVNTHANALL ARFEQSGDVR DLDEAVSAHR SALKPRSPSD
PVPFNSLHNL ASVLFARFNE RGDDKDIDEA ISLQRQALEL RPHTGSDNLP TLRSLAVILM
TRFQRKNNVQ DLDQAISLHR QALECVPAGD PSRVTSIINL STALSSRFDR QGAFEDIDEA
ITLCRQAIDL VSPSYTFYAS LHFNFAGMLS ARFREQGSVS DFNEALATFE KTLTLLPAND
PRRPSALCNF AKLHVVARQK LGQQASVELA VSLLSEATQS PVQSPARRWS CAVQWAQYAD
EHQHPSALEA FEVALAVSAE LAAVGLGVQS HQGTIIERTD ELARRAAQCA INAGDLGKAV
EFLETGRSVF WSKALNLKTP IDQLHDVAPQ LAADLRRIAA GFAQEPHRES NLLSNSQVWA
DSEGGTNALE RLAAEWAEKV GQVRKLDGFE DFLRPKSLST LQSAATERPV VYLVANDSSS
DCLILASGHI HHIPLTTLPA HVLSELVRLV KIGISDPVVA PVLASEAEES GVSRERDDKR
HPSSGDPLGS VLESLWNELV QPVIQSLGLK GLGRKTTLTW CPTGLFSFLP VHAAGRYADA
VVECASQYLI SSYTPTIGAL LMPDHPPVTP FRMMIVVQSH SSPNAMEEMM NIEQHVNNDN
NSLIKFGTSE SPASVEAVAS CLPQASIVHF ACHGKQDPRK PLKSGLVIEN EILTISRIMK
EPLLAGSLAF LSACETATRD ESVIDEAITV GASLMFGGFE RVVATMWRNQ DGPAIANAFY
RELFSGVDGN PMTVPDTSKY AEALSIAVEE LRSRGVEFRR WVPFIHMGK
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