ID A0A409Y6B6_9AGAR Unreviewed; 449 AA.
AC A0A409Y6B6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=COP9 signalosome complex subunit 4 {ECO:0000256|ARBA:ARBA00014881};
GN ORFNames=CVT24_003982 {ECO:0000313|EMBL:PPQ98491.1};
OS Panaeolus cyanescens.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Galeropsidaceae; Panaeolus.
OX NCBI_TaxID=181874 {ECO:0000313|EMBL:PPQ98491.1, ECO:0000313|Proteomes:UP000284842};
RN [1] {ECO:0000313|EMBL:PPQ98491.1, ECO:0000313|Proteomes:UP000284842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2629 {ECO:0000313|EMBL:PPQ98491.1,
RC ECO:0000313|Proteomes:UP000284842};
RX PubMed=30283667; DOI=10.1002/evl3.42;
RA Reynolds H.T., Vijayakumar V., Gluck-Thaler E., Korotkin H.B.,
RA Matheny P.B., Slot J.C.;
RT "Horizontal gene cluster transfer increased hallucinogenic mushroom
RT diversity.";
RL Evol. Lett. 2:88-101(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN4 family.
CC {ECO:0000256|ARBA:ARBA00010417}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPQ98491.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NHTK01001382; PPQ98491.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A409Y6B6; -.
DR STRING; 181874.A0A409Y6B6; -.
DR InParanoid; A0A409Y6B6; -.
DR OrthoDB; 5476188at2759; -.
DR Proteomes; UP000284842; Unassembled WGS sequence.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR040134; PSMD12/CSN4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10855; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR10855:SF2; COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000284842}.
FT DOMAIN 191..390
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 449 AA; 49793 MW; 958C092FF245B9AA CRC64;
MEAKLSQISA LSQKDKGPAF ISLIPEIFSQ PEATISQNLR LLVDTVVNQE SVGLVVGRQV
LSEVVKSLGE GTVSDHDLRK QLVEGTLTIV QPRIVSYEEQ VNSLRFQLAD LLEEEESWSE
AARVLMGISL DSGQRSVGDT DKLKIYVRIV RLLLEDEDSV QAETYYNRAA LLLHSTTDQE
IILQFKLCQA RISDYSRKFL EAASRYHELS YVGEIDEEER RHMLLAAVTC AVLAPAGPNR
SRVLASLYRD ERTADLSTYN ILSKMFLDHI LRSAEVKEFE KTLKPHQLAQ IAISSNDRLA
SAGTAVDDDA DPGASTRTGP STVLDRAVME HNLLASSNIY NNITFRGLGA LLDLTPGAAE
TIARKMIEQG RLRASIDQVD KLIWFEKNRE EDDAQGKAGG LGDVEEAEDT GAPFTKRWDN
HIRLTAAHVE SIVQHLSTKG LLSHDIEVS
//
