ID A0A410K200_9BACT Unreviewed; 366 AA.
AC A0A410K200;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=EP073_01995 {ECO:0000313|EMBL:QAR34449.1};
OS Geovibrio thiophilus.
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Geovibrionaceae; Geovibrio.
OX NCBI_TaxID=139438 {ECO:0000313|EMBL:QAR34449.1, ECO:0000313|Proteomes:UP000287502};
RN [1] {ECO:0000313|EMBL:QAR34449.1, ECO:0000313|Proteomes:UP000287502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11263 {ECO:0000313|EMBL:QAR34449.1,
RC ECO:0000313|Proteomes:UP000287502};
RA Spring S., Bunk B., Sproer C.;
RT "Geovibrio thiophilus DSM 11263, complete genome.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP035108; QAR34449.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A410K200; -.
DR KEGG; gtl:EP073_01995; -.
DR OrthoDB; 9789782at2; -.
DR Proteomes; UP000287502; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:QAR34449.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000287502};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 81..128
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 150..364
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 366 AA; 40887 MW; 3EBDC336CEC53284 CRC64;
MQSNNDGMFR AVGLDGEKRL FGFTTMTGQG TNLRLMVGIP EKLAMEPVKK VFFYIGVWIV
FSTIVLITAW VAGSLFALSK INRLANVTKE LSTGDLSVRT GIRYGRGELG QLAKAFDSMA
EALQERDREL AARTAELERS NEELEQFAYI ASHDLQEPLR MISSYTQLLA KRYKDKLDED
ATEFINYAVD GANRMQVLIN DLLSYSRVGT KGEEFSHVDL NGVLDIVKAN LKGVIEESGA
VIKYSKLPTV LADNSQMLQL FQNLTGNAIK FRREGVKPEI EISAKKEGNM FRFMVKDNGI
GIDKKYLDRI FVIFQRLHTK EEFPGTGIGL AICKKIVERH GGEISVESAE GKGSDFIFTL
QGKGRE
//
