ID   A0A410T6B7_9CAUD        Unreviewed;       446 AA.
AC   A0A410T6B7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=DNA topoisomerase II {ECO:0000313|EMBL:QAU04514.1};
GN   ORFNames=ValB1MD_180 {ECO:0000313|EMBL:QAU04514.1};
OS   Vibrio phage Va1.
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes.
OX   NCBI_TaxID=2508852 {ECO:0000313|EMBL:QAU04514.1, ECO:0000313|Proteomes:UP000289494};
RN   [1] {ECO:0000313|EMBL:QAU04514.1, ECO:0000313|Proteomes:UP000289494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Li C., Zhang Y., Liang Y.;
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type II topoisomerase family.
CC       {ECO:0000256|ARBA:ARBA00011080}.
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DR   EMBL; MK387337; QAU04514.1; -; Genomic_DNA.
DR   Proteomes; UP000289494; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   Gene3D; 3.30.1360.40; -; 1.
DR   Gene3D; 3.90.199.10; Topoisomerase II, domain 5; 1.
DR   Gene3D; 1.10.268.10; Topoisomerase, domain 3; 1.
DR   InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a_sf.
DR   InterPro; IPR002205; Topo_IIA_dom_A.
DR   InterPro; IPR001154; TopoII_euk.
DR   PANTHER; PTHR10169:SF38; DNA TOPOISOMERASE 2; 1.
DR   PANTHER; PTHR10169; DNA TOPOISOMERASE/GYRASE; 1.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   PRINTS; PR01158; TOPISMRASEII.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Isomerase {ECO:0000313|EMBL:QAU04514.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000289494}.
FT   DOMAIN          10..443
FT                   /note="DNA topoisomerase type IIA"
FT                   /evidence="ECO:0000259|SMART:SM00434"
FT   COILED          408..435
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   446 AA;  51972 MW;  2C941C4C585D82AC CRC64;
     MTKTSNMKTV PVEDFYGSDY VDYASYDNLR KIASVVDGQK NAARKVLHTV LEKNIRGKKI
     KVSQIASKVA EYTEYLHGDV SGVIVTMGQD FAGANNLPLL QKSGNFGTRF HNEASASRYI
     HTYGKDVFFE LFKKDDIDIL KQQYFEGQRI EPMFFVPSLP MILINGSDGV SSGFAQKILP
     RNPDKIKQYL TQRLQGKGSY YKFEPYFNGF NGVIEQGENP SQWKIKGVVK RKSINKVEIL
     EVPIGYELKG YLKVLDTLEE KKVIQSYRDK SEDDIFKFEV SIPSKELKEW SDEELLQKLK
     LVKTVTENYT VIDENNKIQV YNSPQEIMDK YIDVKMEYMK LRKENNLARL QEHILFDQSK
     YKFIEMIVND ELIVNKRKKT DIEKDLHKVD EILDRNGSYD YLLNMSISTL TDERMKQLEN
     NIKENQKRLK ELNQKTLEKL WLEDLS
//