ID A0A410UHZ2_9GAMM Unreviewed; 311 AA.
AC A0A410UHZ2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=holB {ECO:0000313|EMBL:QAU23883.1};
GN ORFNames=EO087_07665 {ECO:0000313|EMBL:QAU23883.1};
OS Dyella sp. M7H15-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Rhodanobacteraceae; Dyella.
OX NCBI_TaxID=2501295 {ECO:0000313|EMBL:QAU23883.1, ECO:0000313|Proteomes:UP000288967};
RN [1] {ECO:0000313|EMBL:QAU23883.1, ECO:0000313|Proteomes:UP000288967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M7H15-1 {ECO:0000313|EMBL:QAU23883.1,
RC ECO:0000313|Proteomes:UP000288967};
RA Gao Z.-H., Qiu L.-H., Yang Z.;
RT "Dyella phosphatilytica sp. nov. strain M7H15-1T., a phosphate solubilizing
RT bacterium isolated from forest soil and analysis of the complete genome
RT sequence.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; CP035300; QAU23883.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A410UHZ2; -.
DR KEGG; dye:EO087_07665; -.
DR OrthoDB; 9811073at2; -.
DR Proteomes; UP000288967; Chromosome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:QAU23883.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000288967};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:QAU23883.1}.
SQ SEQUENCE 311 AA; 34326 MW; 8E405EE4B62F2531 CRC64;
MSNPPWHAEH WARLQSRRQR DALPHALLLC GSRGLGKRDF LRRFVRGLLC QHPDNGEACG
TCRSCLLFDA GTHPDYVAMS YGLRKDGVQR SEIVVDQLRE LSARLATASQ FCGWQIASID
PADAMNVAAA NALLKTLEEP ASQTMLILLA DEPWRMPATI RSRCQRIDFP LPAQETSLTW
LQQVGVRDAQ AALAAAGGNP GLARIWAEEG ALTQRQEVRK DLAALAAGRG DAMEMGRRWL
DGAPEQRLWF AAQVVADEMR ARATAQASPL GSTMDIEGLG VWYDAANRAR EALRGPLRGD
LLLLELLGRW R
//
