ID   A0A411HNR9_9GAMM        Unreviewed;       950 AA.
AC   A0A411HNR9;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Formate dehydrogenase {ECO:0000313|EMBL:QBB72131.1};
GN   ORFNames=ELE36_18145 {ECO:0000313|EMBL:QBB72131.1};
OS   Pseudolysobacter antarcticus.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Pseudolysobacter.
OX   NCBI_TaxID=2511995 {ECO:0000313|EMBL:QBB72131.1, ECO:0000313|Proteomes:UP000291562};
RN   [1] {ECO:0000313|EMBL:QBB72131.1, ECO:0000313|Proteomes:UP000291562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AQ6-296 {ECO:0000313|EMBL:QBB72131.1,
RC   ECO:0000313|Proteomes:UP000291562};
RA   Wei Z., Peng F.;
RT   "Pseudolysobacter antarctica gen. nov., sp. nov., isolated from Fildes
RT   Peninsula, Antarctica.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; CP035704; QBB72131.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A411HNR9; -.
DR   KEGG; xbc:ELE36_18145; -.
DR   OrthoDB; 9810782at2; -.
DR   Proteomes; UP000291562; Chromosome.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02783; MopB_CT_2; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.30.200.210; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR   PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291562}.
FT   DOMAIN          28..84
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          922..950
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        932..950
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   950 AA;  105700 MW;  7A2888E1460459A9 CRC64;
     MRFLSPPRAS HSPSMPHADL KLDTPVGDTI KTTTCYMCAC RCGIKVHIKD GRIRYIEGNR
     AHPVNKGVLC AKGSAGIMQH YSPARLRAPL KRIGKRGDGE FEEISWDEAL AIATGWLGDI
     RKTDPDKLAF FTGRDQSQAL TGWWAQAFGT VNYAAHGGFC SVNMAAGGLY SIGGSFWEFG
     EPDWEHSKYL LMFGVAEDHD SNPIKTGLGK LKTRGAKFVA INPVKTGYAA IADEWIGIRP
     ATDGLFVGAL IHELLRNDWV DFDYLVRYAN AHWLVIMAPG ATDDGMFVRD GEGRPLCFDR
     AAKQTTHASA SGIQPAIVGE FILADGRRAM PAFQLLATRF LDAEYAPDAV TERCGISVET
     IKRIAAEIAD VAFNQAIRLP VRWTDSSGVE HEEMLGRPVS FHAMRGIAAH SNGFHTCRML
     HTLQLLLGAV DTPGSFRYQP PFPKPIPPAN RPGRTRRDNG ALDAAPLGFV HGPEDLVVDT
     NGNPRRLDKA FSWEFPLAAH GMLQSVIRNA WAGDPYPIDT LFLFMANMSW NSAMNTTQTM
     HMLTDQHANG EYKIPHIIYS DAYTSEMVAY ADLILPDTTY LERHDCISLL DRPISDADGA
     ADSIRQPVFA PDRDVRPFQD VLLDLGARLQ LPGIVDDFGV AKYPGGFPEY MVKHERAPGI
     GLLAGWRGIA ADKRGIGEPN PEQLKRYIDN GCFWHHEIPE SARYYKMANR DYLAWSKSLG
     FIGSTDPIVL QLYSETLQKF RLAALGHGAQ QPPEKDRARV ARYFDPLPFW YEPFEWSGID
     QNKFPLSALT QRPMFMYHSW GSQNAWLRQI ATRNWLHLHP STAALHGIVD EDWLIVESHH
     GRIEVQAKLH AGVEPNTVWT WNAIGKRRGA WKLSDDAPEH APGFLLNHVI SDVLPDLTYA
     NADPITGQAA WFDLRVRIEK APPRDEESRT IDTSIGSSMA HTKNRPSATT
//