ID A0A411X7D7_9BURK Unreviewed; 872 AA.
AC A0A411X7D7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|ARBA:ARBA00021982, ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096,
GN ECO:0000313|EMBL:QBI04842.1};
GN ORFNames=EYF70_05150 {ECO:0000313|EMBL:QBI04842.1};
OS Pseudoduganella albidiflava.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Pseudoduganella.
OX NCBI_TaxID=321983 {ECO:0000313|EMBL:QBI04842.1, ECO:0000313|Proteomes:UP000292307};
RN [1] {ECO:0000313|EMBL:QBI04842.1, ECO:0000313|Proteomes:UP000292307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17472 {ECO:0000313|EMBL:QBI04842.1,
RC ECO:0000313|Proteomes:UP000292307};
RA Miess H., Frediansyhah A., Gross H.;
RT "Draft Genome Sequences of Six Type Strains of the Genus Massilia.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|ARBA:ARBA00024647,
CC ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
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DR EMBL; CP036401; QBI04842.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A411X7D7; -.
DR KEGG; mali:EYF70_05150; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000292307; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 6.10.140.430; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}.
FT DOMAIN 690..706
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 616..623
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 872 AA; 94996 MW; C0C434FFAC956E75 CRC64;
MMQQYLRIKG EHPTMLVFYR MGDFYELFHE DAEKASRILG ITLTARGHAN GVPIKMAGVP
FHSLDGYLAK LVKLGESCAI CEQIGDPATS KGPVERKVVR IVTPGTLTDS DLLPEKSERP
LLALSMLNVR KQVTCGLAWL SLASGNLKLM EFSGDARAVN GRLQQELERI APAEILRADG
GDLFDAITIC HVNGVPEWHF DVVHGHKALL DQLGVATLTG FGADGMGPAF GAAGALLRYA
QATQGRGLQH VKNLSCETES EFIGLDAATR RNLELTETIR GQEAPTLFSL LDGCRTAMGS
RLLRHWLHHP RRDQAVARGR HDAIAALMQD DATGSLGFHL QQVPDIERIT TRIALLTARP
RDLAALRDGL QQLPKLQKSL ARVAGPESEA ALLRCIHEQL ATPESCVDLL VRAVMPEPAT
MVRDGGVIAR GFDAELDELR GLSENAGQFL VDLEARERAR TGIANLRVEY NRVHGFYIEV
TNGQADKVPE DYRRRQTLKN CERYITPELK AFEDKALSAQ DRALAREKVL YDVLLADLAP
HIGCLQKIAQ GIAQLDTLTA LAEHAMRNNW CAPRLVAESC IDIHEGRHPV VENQIERFIA
NDCRLLAERR LLLITGPNMG GKSTFMRQVA LITLLAYVGS YVPAASATIG PIDRIFTRIG
ATDDLAGGRS TFMVEMTEAA TILNGASEQS LVLMDEIGRG TSTFDGLALA WAIARHLIDT
SRSFTLFATH YFELTQLPES HPTAANVHLS AVEHKDSIVF LHAVQDGPAS QSYGLQVAQL
AGVPQGVIRA ARKHLARLEA QALDATPQLD LFSAPATDAD DQPAMAAAGA AEAAQDPKLA
ALLAALDELD PDALSPREAL DRLYQLKRLV PA
//
