ID A0A413HV34_9FIRM Unreviewed; 454 AA.
AC A0A413HV34;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DXA57_16400 {ECO:0000313|EMBL:RGX96812.1};
OS Blautia sp. OF03-15BH.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=2292287 {ECO:0000313|EMBL:RGX96812.1, ECO:0000313|Proteomes:UP000285119};
RN [1] {ECO:0000313|EMBL:RGX96812.1, ECO:0000313|Proteomes:UP000285119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OF03-15BH {ECO:0000313|EMBL:RGX96812.1,
RC ECO:0000313|Proteomes:UP000285119};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGX96812.1}.
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DR EMBL; QSCM01000028; RGX96812.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A413HV34; -.
DR OrthoDB; 84942at2; -.
DR Proteomes; UP000285119; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR008358; Sig_transdc_His_kin/Pase_MprB.
DR PANTHER; PTHR45528; SENSOR HISTIDINE KINASE CPXA; 1.
DR PANTHER; PTHR45528:SF14; SENSOR HISTIDINE KINASE CSSS; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR01780; LANTIREGPROT.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RGX96812.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000285119};
KW Transferase {ECO:0000313|EMBL:RGX96812.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 241..454
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 454 AA; 51048 MW; 8C1DD17F0C8189EC CRC64;
MGVKKKPTLK ILFRQFAISL IVMLVAAIIV PSGLEGLAVN AGLATRANLS ELQVKEIIPT
LTIAPDITKV VIPQGCGYLI LDKNFNELYS NMDDDEKEIA LLYAKGEYIE YATGRQFALV
VRENEFCVLR YYIGSQFTVS WLPEYFPSPD TLAFILMAVN SLLVIIILTA RFAKNLRTQL
TPLFEATAEV SKQNLDFEVR HAKIKEFEDV LASFSDMKDN LKISLERQWK TEQTQKEQIA
ALAHDLKTPL TVIQGNADLL TETNLDDEQR LYAGYVVESS GQMQSYIQTL IDISRAAVGY
QLHIESIDLP AFMQHLFGYM ESLCRTKEIR LQMNTVSLPQ MLKFDRVLIE RAIMNVISNG
LDYSPQGGTL YVDVQSNNGF VEISVTDEGT GFSKEALCHA QERFYMGDQS RNSKLHFGMG
LYITNSIMEQ HNGQLILENS KETGGAKVTM KLPC
//
