ID A0A415DLI0_9BACT Unreviewed; 928 AA.
AC A0A415DLI0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA {ECO:0000313|EMBL:RHJ78706.1};
GN ORFNames=DW103_14555 {ECO:0000313|EMBL:RHJ78706.1};
OS Parabacteroides sp. AM08-6.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=2292053 {ECO:0000313|EMBL:RHJ78706.1, ECO:0000313|Proteomes:UP000285678};
RN [1] {ECO:0000313|EMBL:RHJ78706.1, ECO:0000313|Proteomes:UP000285678}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM08-6 {ECO:0000313|EMBL:RHJ78706.1,
RC ECO:0000313|Proteomes:UP000285678};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHJ78706.1}.
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DR EMBL; QRMP01000028; RHJ78706.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A415DLI0; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000285678; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000285678};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 589..919
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 928 AA; 103452 MW; 99084445BA1716DC CRC64;
MSENNSIFIK GARINNLKNI DVEIPRDKLV VITGLSGSGK SSLAFDTLYA EGQRRYVESL
SAYARQFLGR MGKPECDYIK GIPPAIAIEQ KVNTRNPRST VGTSTEIYEY LRLLYARIGK
TISPVSGLEV RKHQVNDIVK EVLSYPEGTR FAVYAPVVLP DGRGIKEQLE ILQKEGYTRL
SIHDTVYRIG EVLADDALLS SPVIELLIDR LTVSTDKTLK SRLADSAETA FFEGHDTCLI
RIYTPEGTVV KEYSKKFEAD GMTFEEPSDM MFSFNNPLGA CPTCEGFGKV LGIDENLVVP
DKSLSVFQGA VVCWKGEVMG EWLKEFIARS EKYNFPIHRP YYDLTQKEKD LLWHGAKGLH
GIDDFFKFVE ENLYKIQYRV MQARYRGKTV CPTCKGSRLR PEALYVQVGG KNIAELVTLP
ITEAKAFFEQ LELDENDASV AKRLLTEISN RLQFLLDVGL GYLTLDRLSA SLSGGESQRI
NLATSLGSSL VGSLYILDEP SIGLHSRDTD LLIQVLRQLQ ELGNTVVVVE HDEEIIRAAD
YIIDIGPKAG RLGGEVVYQG DVNNLKTSSN SYTVGYLTGE DKIEVPAFRR LWNNYIEVKG
ARKNNLKGID VKFPLNVMTV VTGVSGSGKS SLVRDIFYEG VKHYLDEAAR LMVDCCGLNG
DMHLVKGIEF VDQNSIGKSS RSNPVTYIGA YDEIRKLFGD QPLAKQMGYS PAYFSFNKEG
GRCEECKGEG KITVEMQFMA DITLECEACH GKRFKSDVLE VEYHGVNIYD MLEMTVNQAI
EFFEQYPGTQ EKKIIRKLKP LQDVGIGYIK LGQTSSTLSG GENQRVKLAY YLGQEKQQPT
LFVFDEPTTG LHFHDIKTLL KAFNALIDKG HTVVIIEHNM DVIKCADYVI DLGPEGGNAG
GNLVCAGTPE EIAMCATSYT GRYLKDKL
//
