ID A0A415DUS0_9FIRM Unreviewed; 206 AA.
AC A0A415DUS0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=RNA polymerase sigma factor SigS {ECO:0000256|ARBA:ARBA00021245};
GN ORFNames=DW099_17440 {ECO:0000313|EMBL:RHJ83987.1};
OS Emergencia timonensis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XIII. Incertae Sedis; Emergencia.
OX NCBI_TaxID=1776384 {ECO:0000313|EMBL:RHJ83987.1, ECO:0000313|Proteomes:UP000284841};
RN [1] {ECO:0000313|EMBL:RHJ83987.1, ECO:0000313|Proteomes:UP000284841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM07-24 {ECO:0000313|EMBL:RHJ83987.1,
RC ECO:0000313|Proteomes:UP000284841};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. Sigma-S contributes to the protection against external
CC stress, thus playing a role in cellular fitness and survival.
CC {ECO:0000256|ARBA:ARBA00024701}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|ARBA:ARBA00007788}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHJ83987.1}.
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DR EMBL; QRMS01000007; RHJ83987.1; -; Genomic_DNA.
DR RefSeq; WP_067533029.1; NZ_QRMS01000007.1.
DR AlphaFoldDB; A0A415DUS0; -.
DR STRING; 1776384.GCA_900086585_00348; -.
DR GeneID; 83002767; -.
DR OrthoDB; 9783788at2; -.
DR Proteomes; UP000284841; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.20.120.1810; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR016371; RNA_pol_sigma-H_factor.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30385:SF1; RNA POLYMERASE SIGMA-H FACTOR; 1.
DR PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR PIRSF; PIRSF002939; RNA_polymerase_sigma-H_factor; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000284841};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 172..199
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS00622"
SQ SEQUENCE 206 AA; 23666 MW; 0BF98C2346D6B153 CRC64;
MENKELNLLS DESIVKMAQE GSSTAYEYLI DKYKELAKIK SKTYFIAGGD NEDVIQEGMI
GIFKAIRDFD EESEASFRTF AELCVNRQII TAIKHANRQK HQILNESVSL SAGEETDSDE
IQSLSEKLAA TSPETDPVSM MLMKEVVDYL KANEQDIFSP FENKVWNEML KGKTYREIAF
RLRRPTKTVD NAMQRIKKKI QSYLEI
//
