ID A0A415DUU7_9FIRM Unreviewed; 515 AA.
AC A0A415DUU7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=M20/M25/M40 family metallo-hydrolase {ECO:0000313|EMBL:RHJ84006.1};
GN ORFNames=DW099_17545 {ECO:0000313|EMBL:RHJ84006.1};
OS Emergencia timonensis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XIII. Incertae Sedis; Emergencia.
OX NCBI_TaxID=1776384 {ECO:0000313|EMBL:RHJ84006.1, ECO:0000313|Proteomes:UP000284841};
RN [1] {ECO:0000313|EMBL:RHJ84006.1, ECO:0000313|Proteomes:UP000284841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM07-24 {ECO:0000313|EMBL:RHJ84006.1,
RC ECO:0000313|Proteomes:UP000284841};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHJ84006.1}.
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DR EMBL; QRMS01000007; RHJ84006.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A415DUU7; -.
DR STRING; 1776384.GCA_900086585_00369; -.
DR OrthoDB; 9761532at2; -.
DR Proteomes; UP000284841; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 2.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43808; ACETYLORNITHINE DEACETYLASE; 1.
DR PANTHER; PTHR43808:SF33; DIPEPTIDASE SAOUHSC_01868-RELATED; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:RHJ84006.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000284841}.
FT DOMAIN 439..501
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
SQ SEQUENCE 515 AA; 57676 MW; 582C2896F3E5AE8F CRC64;
MRNKIDSYIK AKRSEMIEDI LELIRIKSIN GCAAENTEAL NLFLQKAEAM GFKTMKTSTG
DVGIVELGSG DQTLGILVHM DVVGIGDTDK WTYPPFEGRV AKGFLWGRGV VDDKGPAVMC
LYALKAIKEL EIPLNKRVWL IVGTSEEAEW TDIASFKKEF PVPDFGFSPD GDFPIYNSEK
GYCDVQMRFM EPCIDILEKL DSGDSPNTIP SRAEVKIRNQ ENLVFHGISC HSSAPAIGIN
AISKMAVELG YRTEFNFIRF LNDFLAKDYN GEKLGMDKNV HADLTPTQRS IIVPTILKRE
GDKVLLNVNV RSCTGVSKED VIAAFMRQKE KYSFEMELYD FLEPMFVDEK EEFLQVMAEV
YADYGYESSF QSALGTSYAK SMKHFVSFGP VFQTEPSCAH MEDERMSITA MITATQIYTT
YIATMASPIG GIRKNAEKMT SLEKALFLLS LFTDPPYHYD VPGLVELTGM NRTTVYRNLS
TLEKAGLLQK DPTTKAYSLG PLAEKMGEKA NDIRT
//
