ID   A0A415DWB7_9BACT        Unreviewed;      1035 AA.
AC   A0A415DWB7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   03-MAY-2023, entry version 11.
DE   SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:RHJ84797.1};
GN   ORFNames=DW103_04935 {ECO:0000313|EMBL:RHJ84797.1};
OS   Parabacteroides sp. AM08-6.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC   Parabacteroides.
OX   NCBI_TaxID=2292053 {ECO:0000313|EMBL:RHJ84797.1, ECO:0000313|Proteomes:UP000285678};
RN   [1] {ECO:0000313|EMBL:RHJ84797.1, ECO:0000313|Proteomes:UP000285678}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AM08-6 {ECO:0000313|EMBL:RHJ84797.1,
RC   ECO:0000313|Proteomes:UP000285678};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHJ84797.1}.
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DR   EMBL; QRMP01000004; RHJ84797.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A415DWB7; -.
DR   OrthoDB; 9798415at2; -.
DR   Proteomes; UP000285678; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285678};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        357..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..400
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        406..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        451..472
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        484..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        540..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        868..886
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        893..915
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        921..944
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        971..989
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1001..1025
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1035 AA;  113024 MW;  F83DD8CAB1476007 CRC64;
     MKNIIKFAVS NPVTICMVVL AILLLGKISY DQLSVDLLPD LNNPRLFIEL KAGERPPEEI
     EKQFVKNIES LAIRQSDVTQ VSSVIKAGSA RITVEYSWTK DMDEAFLDLQ KAMSPLSQNN
     DITELKITQH DPNQSPVVLV GLSHMNITDM AELRKVAESY IRNELIRLEG VADVTLSGDE
     VSTLTIRTDP YKLEAFKLTI NDISSRVEAN NQSISGGRVS ELGLQYLVKS SSLFSSERDF
     ENLIVGYKAI EAQNTSASSG STATGTVSDG NKAPIFLKEV ASVQFENARP ENIVRINGER
     SIGLSVYKEM RFNTVKVVDA VTRQLGIIEQ ALPGYRFQVI TNQGTFIKNA IGEVKDSAVL
     GIILAVIILF VFLRRFGTTL IVSMAIPISI VATFNLMFFN HLTLNIMTLG GLALGAGMLV
     DNAIVVIESI FRNQEKGMSV KEAAITGTSE VAGAVIASTL TTVVVFLPIV YLHGASGELF
     KDQAWTVTFS LVSSLFVAIL VIPMLYDRIA GRKKEALQEV KSIQMKGYSK LLRKLLEYRW
     GVISAAVLLI VVAGLLTPFI GTEFMPKAES KTFSAVVRLP EGTRLERTAS AIDGLESLLR
     TISGDSLCTV YSHVGPGSGS ENDIFEGENT AVMKVILSPS CPISPDEVMA RFVQATEETE
     GLDITLKQDE NSLSSLLGSE GAPIVVEVKG EELDEIAVLT EEVKGRMMTV NGLYNVRSSI
     EDGAPEVTIS LNRTVAGINN LSVQTVIDQL KQQLSGLETG KMDYRGEMRD ILIKVPDITL
     KDLGMLVIKN GDQEFRLQEV ADIIPSQAPK EIFRRGQNRI SKVMADMDDN QSLDKMAAQI
     RSAVSDIDLP NNYSITVTGE EEKRQESMNS LLFALALSVI LVYMVLASQF ESLLHPFTIL
     LTIPLAVVGA VLLFFLTGTT INMMGVIGIV MLVGIAVNNS IILVDRINQL KTGMPLTDAI
     VEAGQQRIRP ILMTTLTTIL ALLPMTISFG EGASLRSPMA IAVIGGLLTS TLMSLMVIPC
     VYYVLERIKT RKKRI
//