ID   A0A415EK11_9FIRM        Unreviewed;       823 AA.
AC   A0A415EK11;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE   AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN   ORFNames=DW089_05320 {ECO:0000313|EMBL:RHK02125.1};
OS   Acidaminococcus sp. AM05-11.
OC   Bacteria; Bacillota; Negativicutes; Acidaminococcales; Acidaminococcaceae;
OC   Acidaminococcus.
OX   NCBI_TaxID=2291997 {ECO:0000313|EMBL:RHK02125.1, ECO:0000313|Proteomes:UP000285880};
RN   [1] {ECO:0000313|EMBL:RHK02125.1, ECO:0000313|Proteomes:UP000285880}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AM05-11 {ECO:0000313|EMBL:RHK02125.1,
RC   ECO:0000313|Proteomes:UP000285880};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC       {ECO:0000256|ARBA:ARBA00038000}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHK02125.1}.
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DR   EMBL; QRMX01000006; RHK02125.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A415EK11; -.
DR   OrthoDB; 9809851at2; -.
DR   Proteomes; UP000285880; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR   Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041552; UvrA_DNA-bd.
DR   PANTHER; PTHR43152:SF1; UVRA PROTEIN; 1.
DR   PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR   Pfam; PF17755; UvrA_DNA-bind; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          488..818
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
SQ   SEQUENCE   823 AA;  89091 MW;  0EA34534E89EBEE8 CRC64;
     MIQVRGARVH NLKNINVDIP LHKIVGIAGV SGSGKSSLAL GILYAEGSRR YLESLSTYTR
     RRMTQAQRAD VDEVRYVPAA LALHQRPGVP GIRSTFGTLS ELSNSLRLIF SRLASHRCPN
     GHYVPPSLAV AAMQEITCPE CGAKFYGPGA EDLAFNSRGA CPTCGGTGIV RTVNQASLVP
     DENLTIDQGA VVVWGTLMWS LMKEVCREMG VRTDVPFKDL TPKEKWVVYH GPAEKKHILY
     INPKTQQSTE LDFTYYNANY TVENALAKVK DEKGMKRLER FLKEGVCPDC HGSRMSEATR
     APRLRGIGLD QASQMTLDDL VVWVRGVPAS LPEEMRPMAQ SICEAFLDTA KRLRDLGLGY
     LSLDRASGTL STGERQRVQL ARAVRNRTTG VLYVLDEPSI GLHPYNLQGL TAVLDDLVAD
     GNSVVLVDHD TQVLCHSQYL LEMGPGSGAD GGKLVAQGTV AELEQNPQSL IGPYLQKEEK
     PHLLPPGLPQ KELFAKGTLH LATDQLHTVQ PLDVKLPLGR LTVVTGVSGS GKTTLVLESL
     IPALKAAIEG TPLPAHVKSV EAPGISQVKL IDATPIGINV RSTVATYAGI HDELRKVYAR
     TEDAKALGYK AGDFSYNTGK LRCPTCDGTG QISLDVQFLP DVDIPCPDCR GSRYSKEAHA
     IHRKAKDGHS YSLPELMNMS VDQALLACKG LSLLQRRLQV LHDLGLGYLT LGEETPGLSG
     GEAQRLKLAS EMGRGQGDTV FVFDEPTIGL HPKDVETLLG VFHQLLDLGA TVLVIEHDLD
     VIRAADYLVD MGPGGGKAGG RIVAQGTPQE IRSCLDSVTG RFI
//