ID A0A416EFT2_9FIRM Unreviewed; 337 AA.
AC A0A416EFT2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 03-MAY-2023, entry version 11.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:RHP32025.1};
GN ORFNames=DWZ56_14785 {ECO:0000313|EMBL:RHP32025.1};
OS Lachnotalea sp. AF33-28.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnotalea.
OX NCBI_TaxID=2292046 {ECO:0000313|EMBL:RHP32025.1, ECO:0000313|Proteomes:UP000285302};
RN [1] {ECO:0000313|EMBL:RHP32025.1, ECO:0000313|Proteomes:UP000285302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF33-28 {ECO:0000313|EMBL:RHP32025.1,
RC ECO:0000313|Proteomes:UP000285302};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHP32025.1}.
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DR EMBL; QUEE01000010; RHP32025.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A416EFT2; -.
DR OrthoDB; 3180992at2; -.
DR Proteomes; UP000285302; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01542; PBP1_TreR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF134; OPERON REPRESSOR, PUTATIVE-RELATED; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000285302};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..59
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 12..65
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 337 AA; 37046 MW; 34D94C41A9D9A948 CRC64;
MENKESRITK KITIADIADM AGVTKSTVSR YFNGGSVKGS TREKIQEIVK AHDYEPNTFA
RLKASKSNVI GVVLPTLNSK VTSRVITSIG RYLREHGYEA LIKDSDHSSE LERRNIQWLI
AQNVDGILLS AITMSEEHRQ LIHECPVPVV VLAQDYGDGI TVTQDDYGAG RAMGMYIGRS
GPGRVAYLGV NESDAAVGIE RRRGVIDGLK ECGITDILTV TGDYSYQSGQ EMAEAVLKEG
PVDAMICATD RLAFGAYRVL ERHGLNIPDD VSVAGFGGYD ESELLKPQLT TLRFDSYTLG
YLGAETLLKR IRKEPVPKKQ IVDYTLIEGQ SVKIPSR
//
