ID   A0A416ER07_9FIRM        Unreviewed;      1383 AA.
AC   A0A416ER07;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:RHP35630.1};
GN   ORFNames=DWZ56_03825 {ECO:0000313|EMBL:RHP35630.1};
OS   Lachnotalea sp. AF33-28.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Lachnotalea.
OX   NCBI_TaxID=2292046 {ECO:0000313|EMBL:RHP35630.1, ECO:0000313|Proteomes:UP000285302};
RN   [1] {ECO:0000313|EMBL:RHP35630.1, ECO:0000313|Proteomes:UP000285302}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF33-28 {ECO:0000313|EMBL:RHP35630.1,
RC   ECO:0000313|Proteomes:UP000285302};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHP35630.1}.
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DR   EMBL; QUEE01000002; RHP35630.1; -; Genomic_DNA.
DR   OrthoDB; 9774462at2; -.
DR   Proteomes; UP000285302; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17922; DEXHc_LHR-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR045628; Lhr_WH_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF19306; Lhr_WH; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:RHP35630.1};
KW   Hydrolase {ECO:0000313|EMBL:RHP35630.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285302}.
FT   DOMAIN          39..231
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          263..420
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1383 AA;  155155 MW;  0CDF81A35971DBA2 CRC64;
     MKSDYDIEAL EGRWGLSHIT AGWFEETFGG PTKVQEQAWP AIARGEHTLV SAPTGTGKTL
     SAFLVFIDRL KQQARAGELG QELQVIYISP LKSLAGDIRE NLKRPLSGLA ALEEAGESYP
     IEVALRTGDT TQSEREKMLR HPPHILLTTP ESLFLLLTGQ RGQKLLSTAK AVILDELHAM
     IDTKRGAHLM LSLARLDRLC GRNLQRIGLS ATIEPLDVAA AYLAPDPVTV IAPKMGKEIR
     ITVTGPFADE SGNTRKEAVW ENLGLDVYRR CQSSRCVIAF VEGRRNAEKL AYYVNQAAGE
     EFARTHHGSI AKEQRLSVEE DLRSGRLRLL CATSSMELGI DVGAVDQVFQ VGCPFTISST
     MQRLGRAGHN PGRVSVMYMF PRTAPESLFC GMTARTALEG GVEYAHPPMQ CLDILSQHLV
     SMAVGPGYSV DEVMEILPRA YPFAGVTKQD VESVLAMLAG DYEHEQDIPV RPRVLYDRIH
     GRVEGDPYSR MLAVSAGGTI PDKGLYAVKT AGGVKLGELD EEFVYESRKG DAFLLGTFGW
     KIAEIKKDEV IVEPTSPERA RVPFWKGEIK GRPLKTSLAF GRILRELSAA GEEGRLREAL
     QELGLDENAS KATAGFLERQ MEATDVLPDD RTIVVEHFCD HTGSHQMMVH SLFGRQINAP
     LALLLQQAAC RKTGLNVGCV DEENGLLLYP YGEDELPEGL LYELSPENAR PVLEAILPQT
     SLFNITFRYN AARALMMGMR RNGRQPLWLQ RIRSADMLDG IIAKNSHPLV RETRRECVED
     QWDIAGLEYV LNGIRSGMIT VHEVHVEIPS PMSLPLQWQV EAAQMYEYSP TLPSVIETSA
     KDLENAVMIR PEAEDLATVS ERKRLPEDER QLHSLLMAEG DLTAGELEVP IEWLEELTRR
     GRAAYIEPGL WIAMEQQEEY LRALEERDRE ASLHILRRML RYRGPHTAKE ASQRYAVTEE
     EAETLLMELC RMSAAVEQDG VYYHGELYGR ARQRTIQNRR RQVSTLPGRR YAALMAGRVK
     TAASPREQLK KTLQMFSGSA CPAALWETVL FPARVRDYRG AVLDEILSCG EFFWRMGRDG
     NLEFHTFEEL DWDVEFDRSE ELADEEERAV YRALVKRGAS FLQSLAGFAK ERSPFDILME
     LAKKGLVCAD SFQPVRQWLK QDAMKKSPAK QRVSARVKAM NAGRWDVVRP LGRQSMDQLL
     DRAFDRAVIL CRETAAQQDL PWQEALETLR VWEYTGRARR GYYIEGMSGA QFIRDRDFAG
     VTAALEREEK EEIIWLTASD PAQVWGKSLP HRAGRSFLNV AGTAVALAGG EVIAVMERQG
     RVLRVFDGAL LDRAMEAFVH DFRCGRIYAG AKRLMVKEYP ADAAEALKKA GFQKEMQDYV
     YYW
//