ID   A0A416GA71_9BACE        Unreviewed;      1014 AA.
AC   A0A416GA71;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   03-MAY-2023, entry version 11.
DE   SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:RHP62348.1};
GN   ORFNames=DXA74_11505 {ECO:0000313|EMBL:RHP62348.1};
OS   Bacteroides sp. OF04-15BH.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=2292281 {ECO:0000313|EMBL:RHP62348.1, ECO:0000313|Proteomes:UP000284249};
RN   [1] {ECO:0000313|EMBL:RHP62348.1, ECO:0000313|Proteomes:UP000284249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OF04-15BH {ECO:0000313|EMBL:RHP62348.1,
RC   ECO:0000313|Proteomes:UP000284249};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHP62348.1}.
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DR   EMBL; QUEM01000026; RHP62348.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A416GA71; -.
DR   OrthoDB; 9798415at2; -.
DR   Proteomes; UP000284249; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF18; CATION EFFLUX SYSTEM PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000284249};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        336..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        424..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        464..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        523..541
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        855..874
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        881..904
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        910..928
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        956..977
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        983..1005
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1014 AA;  112981 MW;  E431B8401B87E477 CRC64;
     MKNLTKYFLN NKAFSWLILC LFLIGGVLSY VQMGKLEDAP FTIKQAVVTT PYPGASAQEV
     QEQVTDKLEE SIQSLGELYY LKSDNRAGMS KITVYVKKEI RANEMQQLWD KLRRKVNDVQ
     NQLPEGAGPS VVNDDFGDVL GVFYGLSSPT HSYRDMDKEA KKLKDKLLSV QDVARVEIFG
     LPTPVIELEV NPSVLSQSGI TLTQIAQAFE QQNKIVDAGG IETSTNRIRI DTRGVFSNLE
     EIRQLTITGK DGSTYRLADI AQIHESYSRT PRNAMYLNNQ PAIGLAISTV SDGNVVDMAI
     RVKEVLEEAQ KQLPEGYLIS PIYDQGHESD VANQGFIINL ILSVITVVAV LLFFIGIKNG
     FLIGSGLIFS IFGTLIYMNA TGIALQRMSL AAIIIAMGML VDNAIVVYDS ALINMERGMR
     KRPAILKAVS TGAMPLLGAT LIAILTFLPV YLSPHITGEI LSSLFLVIAV SLFLSWVLAI
     TQNVFFIQEF VRRPKQGRQN AELFSGKYYD GFRKLLRGCI RHRYPLIAVL VGLLYLSYIG
     FQTVPKQFMP LLNKQYFTME IWLPEGTSFD RTRAFTYELT DSLSRYPHVR QLSSFIGQTP
     PRFYLANTAY GPQSNYAQIL VETDTPEEAT ALRQHLEQKM PAAYPEALIK VNSFEINSIP
     QALIEARFCG PDPAVLDSLT QVALEVMRKN PHVVRARNEW GNMAPKLCAD YNPVKGGKIQ
     VQRQHMMQSV KSIHDGVTVG VFRDENDQVP VMLYCSSDTE PTLAELRNWP VWNGKQSAPL
     AQVTDSIHIQ WEYPLMRTYN RQLSMAAQCD VAPGHTMSEV HSEIRDEIEK IRLPEGYSFF
     WDSQFKDQGE AMEALFKYFP LALVALIVIL VALFRNFRQP LIIFLVLPLS VIGVVFGLCV
     TGFQFGFFCI AGWLGLLGMI IKNVIVLLDE TNSLKGSGLS DYQAIIEATV SRARPVLMAA
     LTTVFGSIPL LFDVAFGGMA ATIVFGLTFA TLLTLVVTPV LYCIFYRVSP AGGK
//