ID A0A416GG63_9BACE Unreviewed; 644 AA.
AC A0A416GG63;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=RecQ family ATP-dependent DNA helicase {ECO:0000313|EMBL:RHP66256.1};
DE EC=3.6.4.12 {ECO:0000313|EMBL:RHP66256.1};
GN ORFNames=DXA74_03830 {ECO:0000313|EMBL:RHP66256.1};
OS Bacteroides sp. OF04-15BH.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=2292281 {ECO:0000313|EMBL:RHP66256.1, ECO:0000313|Proteomes:UP000284249};
RN [1] {ECO:0000313|EMBL:RHP66256.1, ECO:0000313|Proteomes:UP000284249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OF04-15BH {ECO:0000313|EMBL:RHP66256.1,
RC ECO:0000313|Proteomes:UP000284249};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHP66256.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QUEM01000005; RHP66256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A416GG63; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000284249; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:RHP66256.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:RHP66256.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000284249}.
FT DOMAIN 27..195
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 219..365
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 230..274
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 644 AA; 74042 MW; 1CC674205B08CBCE CRC64;
MTEDKYHIIL KQYWGYDDFR GIQQEIIHSI GSGKDTLGLM PTGGGKSIAF QVPALAQEGI
CIVITPLIAL MKDQVENLKK RGIKAAAIYS GLTHNEILVT LENCIFGDYK FLYVSPERLS
SELFLTKLKR MRVSFITVDE AHCISQWGYD FRPSYIRIAD LRKVVPQAPV LALTATATPE
VVKDIQDKLL FRQEHVFKMS FARKNLAYVV RHTEDKESEL LHIINSIPGT VIVYCRSRKE
CRDLAAQLEE RGLTATFYHA GLSNCEKDER QRLWQTDQCR VMVATNAFGM GIDKPDVRLV
VHMDVPDSPE AYFQEAGRAG RDGRKAYAVL LYNASDKTKL MKRIPDTFPD REFIKEIYEH
ICYYYQMAMG DGLNVTREFN LNEFCRNFKH FPVPTDSALR ILTRAGYLEY IDEQENDSRL
IFLVRRDELY HVDGLEPEYE SLLQAVLRSY GGVFSDYITI DETLLGKQTG LSRDMVYRGL
IALGKRRIIS YIPYKKTPYI RFAQKRVETE RIVISREIYE NRKEKYEARI QAMIDYATRD
DLCRSRMLLA YFGETSEENC LACDVCLKKN SAGISQGLAE NVEKRITALL REQKEVPVHD
IDFPGISRET VGQVLHQMVQ EEKLLLDDGM ISLSPNQDIE ETTN
//
