ID A0A416JRF4_9FIRM Unreviewed; 705 AA.
AC A0A416JRF4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=Glutamine synthetase {ECO:0000256|ARBA:ARBA00021364};
GN ORFNames=DW974_11785 {ECO:0000313|EMBL:RHQ15554.1};
OS Lachnospiraceae bacterium AM48-27BH.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=2292271 {ECO:0000313|EMBL:RHQ15554.1, ECO:0000313|Proteomes:UP000285913};
RN [1] {ECO:0000313|EMBL:RHQ15554.1, ECO:0000313|Proteomes:UP000285913}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM48-27BH {ECO:0000313|EMBL:RHQ15554.1,
RC ECO:0000313|Proteomes:UP000285913};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHQ15554.1}.
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DR EMBL; QUFC01000022; RHQ15554.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A416JRF4; -.
DR Proteomes; UP000285913; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000285913}.
FT DOMAIN 65..159
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 164..595
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 705 AA; 77558 MW; BCFAEA7F15E41A5D CRC64;
MSELVNVAEI FGKNVFNETV MRERLPKSVF KKLKKTIEDG TELDPSIADV VAHAMKDWAI
ERGATHYTHW FQPLTGVTAE KHDSFISAPD SEGKVIMEFS GKELVKGEPD ASSFPSGGLR
ATFEARGYTA WDCTSPAFIR EDALGVTLCI PTAFCSYTGE ALDQKTPLLR SMQAIDEQAL
RILRLFGNTT AKRVVPSVGP EQEYFLVDRA KYLQRKDLIY TGRTLFGAMP PKGQEMDDHY
FGAIPERIGS FMKELNEELW KLGVTAKTQH NEVAPAQHEL APIYDQANLA VDNNQIVMET
MKKVAERHHM TCLLHEKPFA GVNGSGKHNN WSLTSDDGIN LLNPGDTPHE NIQFLLVLAC
IMKAVDIHAD LLREAASDVG NDHRLGANEA PPAIISIFVG DQLEDVIDQL CNTGEATHSK
KGGKLMTGVA TLPDLDKDAT DRNRTSPFAF TGNKFEFRMV GSSDSVAPAN VVLNTIVAES
FKEAADELEK ADDFDMAVHD MIKKLLADHR RIIFNGNGYS DAWVEEAVRR GLPNITSMVD
AIPALTTAKA VKLYEEFGVF TKAELESRAE VEYEAYAKAI NIEAKTMIDM AGKQIIPAVI
KYTTGLADSL GKVKAACPEA DTSVQSELLI ETSALLSDMK VALAALEDIT EESLAIPDAC
LCAHAYHEKV VPAMAALRKP ADELEMLVDK ELWPFPSYGD LIFEV
//
