ID   A0A416R6X1_9FIRM        Unreviewed;       170 AA.
AC   A0A416R6X1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   03-MAY-2023, entry version 11.
DE   SubName: Full=Transcription repressor NadR {ECO:0000313|EMBL:RHR08179.1};
GN   ORFNames=DWX58_10165 {ECO:0000313|EMBL:RHR08179.1};
OS   Pseudoflavonifractor sp. AF19-9AC.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Pseudoflavonifractor.
OX   NCBI_TaxID=2292244 {ECO:0000313|EMBL:RHR08179.1, ECO:0000313|Proteomes:UP000285063};
RN   [1] {ECO:0000313|EMBL:RHR08179.1, ECO:0000313|Proteomes:UP000285063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF19-9AC {ECO:0000313|EMBL:RHR08179.1,
RC   ECO:0000313|Proteomes:UP000285063};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHR08179.1}.
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DR   EMBL; QUGI01000005; RHR08179.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A416R6X1; -.
DR   Proteomes; UP000285063; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   Gene3D; 3.30.1340.20; 3H domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR035922; 3H_dom_sf.
DR   InterPro; IPR004173; 3H_domain.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR026043; NadR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR40068; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   PANTHER; PTHR40068:SF1; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   Pfam; PF02829; 3H; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   PIRSF; PIRSF037847; NiaR; 1.
DR   SUPFAM; SSF75500; Putative transcriptional regulator TM1602, C-terminal domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR037847-1};
KW   Nickel {ECO:0000256|PIRSR:PIRSR037847-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285063}.
FT   DOMAIN          6..58
FT                   /note="Helix-turn-helix type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08279"
FT   DOMAIN          71..167
FT                   /note="3H"
FT                   /evidence="ECO:0000259|Pfam:PF02829"
FT   BINDING         75
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         83
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         142
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         144
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
SQ   SEQUENCE   170 AA;  18329 MW;  90DB0CAE0E62CFA5 CRC64;
     MDGTQRRAEI ARFLSSAKGP VSAAALARKC SVSRQIIVGD IALLRAGGMD IAATPRGYLV
     QRSPSGLVRR VAVRHDGAGM EDELNAMVDQ GCTVLDVIVE HPIYGQLTGP LQLVSRYDVG
     QFIARCRQAE ALPLSQLTEG IHLHTLSCPD QAAYDRVCQS LSKLGFLLED
//